A novel small-molecule compound disrupts influenza A virus PB2 cap-binding and inhibits viral replication.

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Antibody-Dependent Cell-Mediated Cytotoxicity Epitopes on the Hemagglutinin Head Region of Pandemic H1N1 Influenza Virus Play Detrimental Roles in H1N1-Infected Mice The PA Endonuclease Inhibitor RO-7 Protects Mice from Lethal Challenge with Influenza A or B Viruses.

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A novel small-molecule compound disrupts influenza A virus PB2 cap-binding and inhibits viral replication.

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2016 nî lūn-bûn

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2016年论文

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name

A novel small-molecule compoun ...... nd inhibits viral replication.

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type

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A novel small-molecule compoun ...... nd inhibits viral replication.

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A novel small-molecule compoun ...... nd inhibits viral replication.

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A novel small-molecule compoun ...... and inhibits viral replication

@en

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Bo-Jian Zheng

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Jiahui Ye

http://www.w3.org/2001/XMLSchema#string

Jie Zhou

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Kailash Singh

http://www.w3.org/2001/XMLSchema#string

Ke Zhang

http://www.w3.org/2001/XMLSchema#string

Richard Y T Kao

http://www.w3.org/2001/XMLSchema#string

Shuofeng Yuan

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Systematic review of influenza resistance to the neuraminidase inhibitors

Vaccines and antiviral drugs in pandemic preparedness

PatchDock and SymmDock: servers for rigid and symmetric docking.

The structural basis for cap binding by influenza virus polymerase subunit PB2

Structural and Functional Characterization of K339T Substitution Identified in the PB2 Subunit Cap-binding Pocket of Influenza A Virus

New 7-methylguanine derivatives targeting the influenza polymerase PB2 cap-binding domain

Discovery of a novel, first-in-class, orally bioavailable azaindole inhibitor (VX-787) of influenza PB2

Structural insight into cap-snatching and RNA synthesis by influenza polymerase

Re-emergence of fatal human influenza A subtype H5N1 disease

The war against influenza: discovery and development of sialidase inhibitors

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2489-2497

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scholarly article

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10.1093/JAC/DKW194

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English

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Billy Kwok-Chong Chow

Hin Chu

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2016-06-05T00:00:00Z

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27272726

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A novel small-molecule compound disrupts influenza A virus PB2 cap-binding and inhibits viral replication.

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P2860

P2860

A novel small-molecule compound disrupts influenza A virus PB2 cap-binding and inhibits viral replication.

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