Restoration of p53 using the novel MDM2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells.

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A novel small molecule inhibitor of MDM2-p53 (APG-115) enhances radiosensitivity of gastric adenocarcinoma.

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Q52714998-2078940C-DDF2-4086-8759-E0EC1ECE88DA

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Restoration of p53 using the novel MDM2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells.

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Restoration of p53 using the n ...... apillary thyroid cancer cells.

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Restoration of p53 using the n ...... apillary thyroid cancer cells.

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Restoration of p53 using the n ...... apillary thyroid cancer cells.

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P1476

Restoration of p53 using the n ...... apillary thyroid cancer cells.

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Baoxia Li

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Dajun Yang

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Dingyuan Luo

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Haibo Chen

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Hanjie Yi

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Hong Zhang

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Jing Wang

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Lin Zhang

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Miaozhen Qiu

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Ningyi Jiang

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P2860

Synergistic tumor suppression by coexpression of FHIT and p53 coincides with FHIT-mediated MDM2 inactivation and p53 stabilization in human non-small cell lung cancer cells

Treatment of advanced thyroid cancer with targeted therapies: ten years of experience

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MDM2 small-molecule antagonist RG7112 activates p53 signaling and regresses human tumors in preclinical cancer models

Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer

The BRAFV600E oncogene induces transforming growth factor beta secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer

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Blinded by the Light: The Growing Complexity of p53

Discovery of 4-((3'R,4'S,5'R)-6″-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2″-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3″-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic Acid (AA-115/APG-115): A Potent and Orally Active Murine Double

Korea's thyroid-cancer "epidemic"--screening and overdiagnosis.

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43008-43022

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scholarly article

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10.18632/ONCOTARGET.17398

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English

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2017-04-24T00:00:00Z

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Restoration of p53 using the novel MDM2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells.

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P2860

P2860

Restoration of p53 using the novel MDM2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells.

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P1476

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