Tumour-specific proline vulnerability uncovered by differential ribosome codon reading.
about
RNA-Sequencing data supports the existence of novel VEGFA splicing events but not of VEGFAxxxb isoforms.Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation.Insights into the mechanisms of eukaryotic translation gained with ribosome profilingCollecting duct carcinoma of the kidney is associated with CDKN2A deletion and SLC family gene up-regulation.TGFβ1-induced leucine limitation uncovered by differential ribosome codon reading.Resolving the cofactor-binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1.Proteome complexity and the forces that drive proteome imbalance.Targeting amino acid metabolism for cancer therapy.Understanding the Intersections between Metabolism and Cancer Biology.The Growing Toolbox for Protein Synthesis Studies.RiboProfiling: a Bioconductor package for standard Ribo-seq pipeline processing.Monitoring amino acid deficiencies in cancerRibosome Footprint Profiling of Translation throughout the Genome.Genomic profiling of collecting duct renal carcinomaCodon optimality controls differential mRNA translation during amino acid starvation.Site-specific selection reveals selective constraints and functionality of tumor somatic mtDNA mutations.DEPDC5 deficiency contributes to resistance to leucine starvation via p62 accumulation in hepatocellular carcinoma.Computational resources for ribosome profiling: from database to Web server and software.Determination of candidate metabolite biomarkers associated with recurrence of HCV-related hepatocellular carcinoma.Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.Asparagine bioavailability governs metastasis in a model of breast cancer.The exon-intron gene structure upstream of the initiation codon predicts translation efficiency.The Proline Cycle As a Potential Cancer Therapy Target.LncRNA-OIS1 regulates DPP4 activation to modulate senescence induced by RAS.Biosynthetic energy cost for amino acids decreases in cancer evolutionThe Influence of Metabolism on Drug Response in Cancer
P2860
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P2860
Tumour-specific proline vulnerability uncovered by differential ribosome codon reading.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Tumour-specific proline vulnerability uncovered by differential ribosome codon reading.
@en
type
label
Tumour-specific proline vulnerability uncovered by differential ribosome codon reading.
@en
prefLabel
Tumour-specific proline vulnerability uncovered by differential ribosome codon reading.
@en
P2093
P2860
P50
P356
P1433
P1476
Tumour-specific proline vulnerability uncovered by differential ribosome codon reading
@en
P2093
Alejandro Pineiro Ugalde
Ingrid Hofland
Jelle Wesseling
Jelle Zijlstra
Joachim F Oude Vrielink
Levi C M Buil
Olaf van Tellingen
Pieter van Breugel
P2860
P2888
P304
P356
10.1038/NATURE16982
P407
P577
2016-02-15T00:00:00Z
P6179
1006564635