about
Mechanisms of chemical carcinogenesis in the kidneysCarcinogens induce loss of the primary cilium in human renal proximal tubular epithelial cells independently of effects on the cell cycleCystine accumulation attenuates insulin release from the pancreatic β-cell due to elevated oxidative stress and decreased ATP levels.Identification of β2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods.Cyclosporine A-induced renal fibrosis: a role for epithelial-mesenchymal transition.E2A proteins: regulators of cell phenotype in normal physiology and disease.Salmon HNF1: cDNA sequence, evolution, tissue specificity and binding to the salmon serum albumin promoter.New developments concerning the proximal tubule in diabetic nephropathy: in vitro models and mechanisms.Reactive carbonyl compounds impair wound healing by vimentin collapse and loss of the primary cilium.Tacrolimus Modulates TGF-β Signaling to Induce Epithelial-Mesenchymal Transition in Human Renal Proximal Tubule Epithelial CellsLysosomal cystine accumulation promotes mitochondrial depolarization and induction of redox-sensitive genes in human kidney proximal tubular cells.Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.High-Throughput Proteomic Approaches to the Elucidation of Potential Biomarkers of Chronic Allograft Injury (CAI).Cystine dimethylester loading promotes oxidative stress and a reduction in ATP independent of lysosomal cystine accumulation in a human proximal tubular epithelial cell line.Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells.Activation of the beta globin locus by transcription factors and chromatin modifiers.Cyclosporine A--induced oxidative stress in human renal mesangial cells: a role for ERK 1/2 MAPK signaling.Transcriptomic alterations induced by Ochratoxin A in rat and human renal proximal tubular in vitro models and comparison to a rat in vivo model.TGF-β1 mediates sirolimus and cyclosporine A-induced alteration of barrier function in renal epithelial cells via a noncanonical ERK1/2 signaling pathway.Metabolic response to low-level toxicant exposure in a novel renal tubule epithelial cell system.Inter-laboratory comparison of human renal proximal tubule (HK-2) transcriptome alterations due to Cyclosporine A exposure and medium exhaustion.A proteomic approach to immune-mediated epithelial-mesenchymal transition.Protein kinase C beta overexpression induces fibrotic effects in human proximal tubular epithelial cells.Overexpression of E2A proteins induces epithelial-mesenchymal transition in human renal proximal tubular epithelial cells suggesting a potential role in renal fibrosis.Cyclosporine A induced epithelial-mesenchymal transition in human renal proximal tubular epithelial cells.TNF-alpha and IL-1beta-mediated regulation of MMP-9 and TIMP-1 in renal proximal tubular cells.Sirolimus enhances cyclosporine a-induced cytotoxicity in human renal glomerular mesangial cellsUrinary biomarkers of chronic allograft nephropathy.The role of MAPK in drug-induced kidney injury.Deletion of a region that is a candidate for the difference between the deletion forms of hereditary persistence of fetal hemoglobin and deltabeta-thalassemia affects beta- but not gamma-globin gene expression.Identification of novel indicators of cyclosporine A nephrotoxicity in a CD-1 mouse model.Identification of Apolipoprotein AI as a serum biomarker of chronic kidney disease in liver transplant recipients, using proteomic techniques.Sirolimus and cyclosporine A alter barrier function in renal proximal tubular cells through stimulation of ERK1/2 signaling and claudin-1 expression.RhoA and Rho kinase mediate cyclosporine A and sirolimus-induced barrier tightening in renal proximal tubular cells.Identification of the multifaceted chemopreventive activity of curcumin against the carcinogenic potential of the food additive, KBrO3.Sequence analysis and tissue expression of a non-Bohr beta-globin cDNA from Atlantic salmon.Structural organization and sequence analysis of the globin locus in Atlantic salmon.Tail-to-tail orientation of the Atlantic salmon alpha- and beta-globin genes.Functional and comparative analysis of globin loci in pufferfish and humans.Role for TGF-beta in cyclosporine-induced modulation of renal epithelial barrier function.
P50
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P50
description
hulumtuese
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onderzoeker
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հետազոտող
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name
Tara McMorrow
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Tara McMorrow
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Tara McMorrow
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Tara McMorrow
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Tara McMorrow
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Tara McMorrow
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Tara McMorrow
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Tara McMorrow
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Tara McMorrow
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Tara McMorrow
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Tara McMorrow
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Tara McMorrow
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Tara McMorrow
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Tara McMorrow
@fr
Tara McMorrow
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P106
P21
P31
P496
0000-0002-9639-6358