Inactivation of class II transactivator by DNA methylation and histone deacetylation associated with absence of HLA-DR induction by interferon-gamma in haematopoietic tumour cells.
about
Exploiting tumor epigenetics to improve oncolytic virotherapyExpression regulation of major histocompatibility complex class I and class II encoding genesUp-regulation of HLA class-I antigen expression and antigen-specific CTL response in cervical cancer cells by the demethylating agent hydralazine and the histone deacetylase inhibitor valproic acidLack of HLA class II antigen expression in microsatellite unstable colorectal carcinomas is caused by mutations in HLA class II regulatory genes.Decreased major histocompatibility complex class II expression in diffuse large B-cell lymphoma does not correlate with CpG methylation of class II transactivator promoters III and IV.Expression of the MHC class II transactivator (CIITA) type IV promoter in B lymphocytes and regulation by IFN-gamma.Epigenetic Alterations in Fanconi Anaemia: Role in Pathophysiology and Therapeutic Potential.MHC class II transactivator (CIITA) expression is upregulated in multiple myeloma cells by IFN-gamma.Methylation of CIITA promoter IV causes loss of HLA-II inducibility by IFN-gamma in promyelocytic cells.HLA antigen changes in malignant cells: epigenetic mechanisms and biologic significanceCML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression.Histone deacetylase inhibitors activate CIITA and MHC class II antigen expression in diffuse large B-cell lymphoma.HLA class II antigen-processing pathway in tumors: Molecular defects and clinical relevance.Loss of interferon-gamma inducibility of the MHC class II antigen processing pathway in head and neck cancer: evidence for post-transcriptional as well as epigenetic regulation.CIITA methylation and decreased levels of HLA-DR in tumour progression.Hydralazine target: from blood vessels to the epigenome.
P2860
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P2860
Inactivation of class II transactivator by DNA methylation and histone deacetylation associated with absence of HLA-DR induction by interferon-gamma in haematopoietic tumour cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Inactivation of class II trans ...... n haematopoietic tumour cells.
@en
type
label
Inactivation of class II trans ...... n haematopoietic tumour cells.
@en
prefLabel
Inactivation of class II trans ...... n haematopoietic tumour cells.
@en
P2093
P2860
P356
P1476
Inactivation of class II trans ...... n haematopoietic tumour cells.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.BJC.6601602
P407
P577
2004-02-01T00:00:00Z
P5875
P6179
1041775993