Tankyrase Inhibition Causes Reversible Intestinal Toxicity in Mice with a Therapeutic Index < 1.
about
Targeting Tankyrase to Fight WNT-dependent Tumours.Wnt Signaling and Colorectal Cancer.Wnt/beta-catenin pathway: modulating anticancer immune response.Delivery of the Porcupine Inhibitor WNT974 in Mice.Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors.Targeting the Wnt/beta-catenin pathway in cancer: Update on effectors and inhibitors.Regulation of Wnt/β-catenin signalling by tankyrase-dependent poly(ADP-ribosyl)ation and scaffolding.Therapeutic strategies against cancer stem cells in human colorectal cancer.The tankyrase inhibitor G007-LK inhibits small intestine LGR5+ stem cell proliferation without altering tissue morphology.Thoughts on investigational hedgehog pathway inhibitors for the treatment of cancer.Novel molecular insights and new therapeutic strategies in osteosarcomaTankyrases maintain homeostasis of intestinal epithelium by preventing cell death
P2860
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P2860
Tankyrase Inhibition Causes Reversible Intestinal Toxicity in Mice with a Therapeutic Index < 1.
description
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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name
Tankyrase Inhibition Causes Re ...... with a Therapeutic Index < 1.
@en
type
label
Tankyrase Inhibition Causes Re ...... with a Therapeutic Index < 1.
@en
prefLabel
Tankyrase Inhibition Causes Re ...... with a Therapeutic Index < 1.
@en
P2093
P2860
P356
P1476
Tankyrase Inhibition Causes Re ...... with a Therapeutic Index < 1.
@en
P2093
Amy Sambrone
Dolores Diaz
Eric Harstad
Jason Boggs
Mark Merchant
Melissa Schutten
Mike Costa
Paula Katavolos
P2860
P304
P356
10.1177/0192623315621192
P407
P577
2015-12-20T00:00:00Z