The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration.
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Tension on JAM-A activates RhoA via GEF-H1 and p115 RhoGEF.F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signallingHow leukocytes trigger opening and sealing of gaps in the endothelial barrierThe regulation of transendothelial migration: new knowledge and new questionsIntercellular adhesion molecule-1 augments myoblast adhesion and fusion through homophilic trans-interactionsN-glycosylation controls the function of junctional adhesion molecule-A.Using magnets and magnetic beads to dissect signaling pathways activated by mechanical tension applied to cellsGenes, pathways, and animal models in primary open-angle glaucoma.Membrane-bound ICAM-1 contributes to the onset of proinvasive tumor stroma by controlling acto-myosin contractility in carcinoma-associated fibroblasts.Localized signals that regulate transendothelial migration.Recent insights into endothelial control of leukocyte extravasation.Endothelial CD2AP Binds the Receptor ICAM-1 To Control Mechanosignaling, Leukocyte Adhesion, and the Route of Leukocyte Diapedesis In Vitro.Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads.Cell-cell junctional mechanotransduction in endothelial remodeling.Leukocyte transendothelial migration: A local affair.Endothelial cell-cell adhesion and signaling.Hypotheses of cancer weakening and origin.Three-dimensional forces exerted by leukocytes and vascular endothelial cells dynamically facilitate diapedesis.RSK2 drives cell motility by serine phosphorylation of LARG and activation of Rho GTPases.Go with the flow: GEF-H1 mediated shear stress mechanotransduction in neutrophils.
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P2860
The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
The RhoA guanine nucleotide ex ...... te transendothelial migration.
@en
type
label
The RhoA guanine nucleotide ex ...... te transendothelial migration.
@en
prefLabel
The RhoA guanine nucleotide ex ...... te transendothelial migration.
@en
P2093
P2860
P356
P1476
The RhoA guanine nucleotide ex ...... ate transendothelial migration
@en
P2093
E Timothy O'Brien
Elizabeth C Lessey-Morillon
Elizabeth Monaghan-Benson
Keith Burridge
Lukas D Osborne
P2860
P304
P356
10.4049/JIMMUNOL.1302525
P407
P577
2014-02-28T00:00:00Z