The road to avibactam: the first clinically useful non-β-lactam working somewhat like a β-lactam.
about
Cyclic Boronates Inhibit All Classes of β-Lactamases.NMR-filtered virtual screening leads to non-metal chelating metallo-β-lactamase inhibitorsPart II: new frontiers in antibacterial drug discovery.Structural/mechanistic insights into the efficacy of non-classical β-lactamase inhibitors against extensively drug resistant Stenotrophomonas maltophilia clinical isolates.Reversible inactivation of a peptidoglycan transpeptidase by a β-lactam antibiotic mediated by β-lactam-ring recyclization in the enzyme active site.19 F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-β-Lactamase.Cyclobutanone Mimics of Intermediates in Metallo-β-Lactamase Catalysis.Welcome to Future Medicinal Chemistry volume 10.13C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions.Pharmacodynamics of ceftazidime/avibactam against extracellular and intracellular forms of Pseudomonas aeruginosa.Exploring Additional Dimensions of Complexity in Inhibitor Design for Serine β-Lactamases: Mechanistic and Intra- and Inter-molecular Chemistry Approaches.Crystallographic analyses of isoquinoline complexes reveal a new mode of metallo-β-lactamase inhibition.The Infinity War: How to Cope with Carbapenem-resistantTackling the Antibiotic Resistance Caused by Class A -Lactamases through the Use of -Lactamase Inhibitory ProteinRoles of 2-oxoglutarate oxygenases and isopenicillin N synthase in β-lactam biosynthesisSynthesis of a bicyclic oxo-γ-lactam from a simple caprolactam derivative
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The road to avibactam: the first clinically useful non-β-lactam working somewhat like a β-lactam.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
The road to avibactam: the fir ...... king somewhat like a β-lactam.
@en
type
label
The road to avibactam: the fir ...... king somewhat like a β-lactam.
@en
prefLabel
The road to avibactam: the fir ...... king somewhat like a β-lactam.
@en
P2860
P50
P356
P1476
The road to avibactam: the fir ...... king somewhat like a β-lactam.
@en
P2093
Jürgen Brem
P2860
P304
P356
10.4155/FMC-2016-0078
P577
2016-06-21T00:00:00Z