Targeting adipose tissue in the treatment of obesity-associated diabetes. - Wikidata - awgldk - TriplyDB

Targeting adipose tissue in the treatment of obesity-associated diabetes.

Targeting adipose tissue in the treatment of obesity-associated diabetes.

http://www.wikidata.org/entity/Q38852204

about

Biology of Beige Adipocyte and Possible Therapy for Type 2 Diabetes and Obesity Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis The Role of the Growth Hormone/Insulin-Like Growth Factor System in Visceral Adiposity.Total control of fat cells from adipogenesis to apoptosis using a xanthene analog.Loss of PI3K p110α in the Adipose Tissue Results in Infertility and Delayed Puberty Onset in Male Mice.Vascular Endothelial Regulation of Obesity-Associated Insulin Resistance.Impact of Growth Hormone on Regulation of Adipose Tissue.Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming Obesity and Cancer Metabolism: A Perspective on Interacting Tumor-Intrinsic and Extrinsic Factors Endogenous lipid antigens for invariant Natural Killer T cells hold the reins in adipose tissue homeostasis.Regulators of mitochondrial quality control differ in subcutaneous fat of metabolically healthy and unhealthy obese monkeys.Curcumin represses mouse 3T3-L1 cell adipogenic differentiation via inhibiting miR-17-5p and stimulating the Wnt signalling pathway effector Tcf7l2.Macrophage alternative activation confers protection against lipotoxicity-induced cell death Natural alkaloid bouchardatine ameliorates metabolic disorders in high-fat diet-fed mice by stimulating the sirtuin 1/liver kinase B-1/AMPK axis.Folic acid prevents cardiac dysfunction and reduces myocardial fibrosis in a mouse model of high-fat diet-induced obesity.KRAS, YAP, and obesity in pancreatic cancer: A signaling network with multiple loops.FGF21 mimetic antibody stimulates UCP1-independent brown fat thermogenesis via FGFR1/βKlotho complex in non-adipocytes.Purinergic Receptors in Adipose Tissue As Potential Targets in Metabolic Disorders.CK2 modulates adipocyte insulin-signaling and is up-regulated in human obesity.Resveratrol inhibits obesity-associated adipose tissue dysfunction and tumor growth in a mouse model of postmenopausal claudin-low breast cancer.The primary cilium is necessary for the differentiation and the maintenance of human adipose progenitors into myofibroblasts.Adaptive Immunity and Metabolic Health: Harmony Becomes Dissonant in Obesity and Aging.Foxc2 coordinates inflammation and browning of white adipose by leptin-STAT3-PRDM16 signal in mice.Canagliflozin, an SGLT2 inhibitor, attenuates the development of hepatocellular carcinoma in a mouse model of human NASH.Scaffold-free generation of uniform adipose spheroids for metabolism research and drug discovery.A history of obesity leaves an inflammatory fingerprint in liver and adipose tissue.The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis.Understanding Key Mechanisms of Exercise-Induced Cardiac Protection to Mitigate Disease: Current Knowledge and Emerging Concepts.Leptin and brain-adipose crosstalks.Diabetes Mellitus and Obesity as Risk Factors for Pancreatic Cancer.Chronic kidney disease promotes chronic inflammation in visceral white adipose tissue.Groundsel Bush (Baccharis halimifolia) Extract Promotes Adipocyte Differentiation In Vitro and Increases Adiponectin Expression in Mature Adipocytes.Homeobox a5 Promotes White Adipose Tissue Browning Through Inhibition of the Tenascin C/Toll-Like Receptor 4/Nuclear Factor Kappa B Inflammatory Signaling in Mice.Brown adipose tissue derived ANGPTL4 controls glucose and lipid metabolism and regulates thermogenesis.PPARγ and its Role in Adipocyte Homeostasis and Thiazolidinedione-Mediated Insulin Sensitization.TRAIL Deletion Prevents Liver, but Not Adipose Tissue, Inflammation during Murine Diet-Induced Obesity.Effects of marine collagen peptides on glucose metabolism and insulin resistance in type 2 diabetic rats.Insulin action and resistance in obesity and type 2 diabetes.Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate.Epoxygenase inactivation exacerbates diet and aging-associated metabolic dysfunction resulting from impaired adipogenesis.

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Targeting adipose tissue in the treatment of obesity-associated diabetes.

http://www.wikidata.org/entity/Q38852204

description

2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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2016年论文

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name

Targeting adipose tissue in the treatment of obesity-associated diabetes.

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Targeting adipose tissue in the treatment of obesity-associated diabetes.

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Targeting adipose tissue in the treatment of obesity-associated diabetes.

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Nature Reviews Drug Discovery

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Targeting adipose tissue in the treatment of obesity-associated diabetes.

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Christine M Kusminski

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Perry E Bickel

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Philipp E Scherer

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P2860

Evidence against a beneficial effect of irisin in humans

Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

Repurposing metformin: an old drug with new tricks in its binding pockets

Positional cloning of the mouse obese gene and its human homologue

Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions

Reversal of hypertriglyceridemia, fatty liver disease, and insulin resistance by a liver-targeted mitochondrial uncoupler

T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin

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639-660

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scholarly article

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10.1038/NRD.2016.75

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9

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15

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2016-06-03T00:00:00Z

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27256476

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