Functional role of BLAP75 in BLM-topoisomerase IIIalpha-dependent holliday junction processing. - Wikidata - awgldk - TriplyDB

Functional role of BLAP75 in BLM-topoisomerase IIIalpha-dependent holliday junction processing.

Functional role of BLAP75 in BLM-topoisomerase IIIalpha-dependent holliday junction processing.

http://www.wikidata.org/entity/Q38868282

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Human topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1 Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair The RecQ DNA helicases in DNA repair More complexity to the Bloom's syndrome complex RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome Structure and Cellular Roles of the RMI Core Complex from the Bloom Syndrome Dissolvasome Crystal structures of RMI1 and RMI2, two OB-fold regulatory subunits of the BLM complex Decatenation of DNA by the S. cerevisiae Sgs1-Top3-Rmi1 and RPA complex: a mechanism for disentangling chromosomes.Oligonucleotide/oligosaccharide-binding fold proteins: a growing family of genome guardians Topoisomerase 3alpha and RMI1 suppress somatic crossovers and are essential for resolution of meiotic recombination intermediates in Arabidopsis thaliana RMI1 deficiency in mice protects from diet and genetic-induced obesity Unwinding protein complexes in ALTernative telomere maintenance.The Arabidopsis BLAP75/Rmi1 homologue plays crucial roles in meiotic double-strand break repair.Identification of Trypanosoma brucei RMI1/BLAP75 homologue and its roles in antigenic variation.Rmi1 stimulates decatenation of double Holliday junctions during dissolution by Sgs1-Top3.PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution.BLM and RMI1 alleviate RPA inhibition of TopoIIIα decatenase activity The dissolution of double Holliday junctions.Role of replication protein A in double holliday junction dissolution mediated by the BLM-Topo IIIα-RMI1-RMI2 protein complex Multifaceted role of the Topo IIIα-RMI1-RMI2 complex and DNA2 in the BLM-dependent pathway of DNA break end resection.Different expression of alternative lengthening of telomere (ALT)-associated proteins/mRNAs in osteosarcoma cell lines.RMI1 promotes DNA replication fork progression and recovery from replication fork stress Accumulation and Phosphorylation of RecQ-Mediated Genome Instability Protein 1 (RMI1) at Serine 284 and Serine 292 during Mitosis.The BLM dissolvasome in DNA replication and repair.Synthesis and dissolution of hemicatenanes by type IA DNA topoisomerases.Genome instability and embryonic developmental defects in RMI1 deficient mice.The RTR complex as caretaker of genome stability and its unique meiotic function in plants.Helicase-appended topoisomerases: new insight into the mechanism of directional strand transfer.Promotion and regulation of homologous recombination by DNA helicases.Quality control of homologous recombination.Molecular mechanism of double Holliday junction dissolution.Different functions for the domains of the Arabidopsis thaliana RMI1 protein in DNA cross-link repair, somatic and meiotic recombination Arginine methylation facilitates the recruitment of TOP3B to chromatin to prevent R loop accumulation.Loss of Bloom syndrome protein destabilizes human gene cluster architecture.Roles of DNA helicases in the mediation and regulation of homologous recombination.Single-stranded DNA catenation mediated by human EVL and a type I topoisomerase.Defining the roles of the N-terminal region and the helicase activity of RECQ4A in DNA repair and homologous recombination in Arabidopsis.RMI1 and TOP3α limit meiotic CO formation through their C-terminal domains Pathways for Holliday junction processing during homologous recombination in Saccharomyces cerevisiae.

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Functional role of BLAP75 in BLM-topoisomerase IIIalpha-dependent holliday junction processing.

http://www.wikidata.org/entity/Q38868282

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Functional role of BLAP75 in B ...... holliday junction processing.

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type

label

Functional role of BLAP75 in B ...... holliday junction processing.

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prefLabel

Functional role of BLAP75 in B ...... holliday junction processing.

@en

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Journal of Biological Chemistry

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Functional role of BLAP75 in B ...... holliday junction processing.

@en

P2093

Amom Ruhikanta Meetei

http://www.w3.org/2001/XMLSchema#string

Lucy Lu

http://www.w3.org/2001/XMLSchema#string

Patrick Sung

http://www.w3.org/2001/XMLSchema#string

Steven Raynard

http://www.w3.org/2001/XMLSchema#string

Valeria Busygina

http://www.w3.org/2001/XMLSchema#string

Weixing Zhao

http://www.w3.org/2001/XMLSchema#string

Wendy Bussen

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Yang-Yang Ding

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P2860

BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity

The Bloom's syndrome gene product is homologous to RecQ helicases

BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates

A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

The Bloom's syndrome gene product promotes branch migration of holliday junctions

RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments

Yeast Rmi1/Nce4 controls genome stability as a subunit of the Sgs1-Top3 complex.

Binding and activation of DNA topoisomerase III by the Rmi1 subunit.

RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex

Nucleic acid recognition by OB-fold proteins

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15701-15708

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scholarly article

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10.1074/JBC.M802127200

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23

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283

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2414273

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