Emergence of a dhfr mutation conferring high-level drug resistance in Plasmodium falciparum populations from southwest Uganda.
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Influence of malaria transmission intensity and the 581G mutation on the efficacy of intermittent preventive treatment in pregnancy: systematic review and meta-analysisTemporal changes in prevalence of molecular markers mediating antimalarial drug resistance in a high malaria transmission setting in UgandaMolecular evidence of increased resistance to anti-folate drugs in Plasmodium falciparum in North-East India: a signal for potential failure of artemisinin plus sulphadoxine-pyrimethamine combination therapyDeclining trend of Plasmodium falciparum dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant alleles after the withdrawal of Sulfadoxine-Pyrimethamine in North Western EthiopiaHigh-level Plasmodium falciparum sulfadoxine-pyrimethamine resistance with the concomitant occurrence of septuple haplotype in TanzaniaLow-grade sulfadoxine-pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, AngolaOrigin and evolution of sulfadoxine resistant Plasmodium falciparumHigh resistance of Plasmodium falciparum to sulphadoxine/pyrimethamine in northern Tanzania and the emergence of dhps resistance mutation at Codon 581Multiple origins and regional dispersal of resistant dhps in African Plasmodium falciparum malariaThe transit phase of migration: circulation of malaria and its multidrug-resistant forms in AfricaMolecular correlates of high-level antifolate resistance in Rwandan children with Plasmodium falciparum malaria.Travel and the emergence of high-level drug resistance in Plasmodium falciparum in southwest Uganda: results from a population-based study.Experimental validation of FINDSITE(comb) virtual ligand screening results for eight proteins yields novel nanomolar and micromolar binders.Protective efficacy of intermittent preventive treatment of malaria in infants (IPTi) using sulfadoxine-pyrimethamine and parasite resistance.Independent origin of plasmodium falciparum antifolate super-resistance, Uganda, Tanzania, and Ethiopia.Effect of trimethoprim-sulphamethoxazole on the risk of malaria in HIV-infected Ugandan children living in an area of widespread antifolate resistanceIncreased prevalence of the pfdhfr/phdhps quintuple mutant and rapid emergence of pfdhps resistance mutations at codons 581 and 613 in Kisumu, Kenya.Plasmodium falciparum and Plasmodium vivax genotypes and efficacy of intermittent preventive treatment in Papua New GuineaMolecular monitoring of resistant dhfr and dhps allelic haplotypes in Morogoro and Mvomero districts in south eastern Tanzania.Drug resistance maps to guide intermittent preventive treatment of malaria in African infants.In vitro susceptibility to pyrimethamine of DHFR I164L single mutant Plasmodium falciparumThe evolution of pyrimethamine resistant dhfr in Plasmodium falciparum of south-eastern Tanzania: comparing selection under SP alone vs SP+artesunate combination.Reduced impact of pyrimethamine drug pressure on Plasmodium malariae dihydrofolate reductase gene.Drug resistance associated genetic polymorphisms in Plasmodium falciparum and Plasmodium vivax collected in Honduras, Central America.Prevalence of Plasmodium falciparum resistance markers to sulfadoxine-pyrimethamine among pregnant women receiving intermittent preventive treatment for malaria in UgandaTemporal trends of sulphadoxine-pyrimethamine (SP) drug-resistance molecular markers in Plasmodium falciparum parasites from pregnant women in western Kenya.Lack of effect of intermittent preventive treatment for malaria in pregnancy and intense drug resistance in western Uganda.Molecular epidemiology of drug resistance markers of Plasmodium falciparum in Yunnan Province, China.Therapeutic efficacy of artesunate in the treatment of uncomplicated Plasmodium falciparum malaria and anti-malarial, drug-resistance marker polymorphisms in populations near the China-Myanmar border.Application of Serological Tools and Spatial Analysis to Investigate Malaria Transmission Dynamics in Highland Areas of Southwest Uganda.Chloroquine resistance before and after its withdrawal in Kenya.Decreasing efficacy of antimalarial combination therapy in Uganda is explained by decreasing host immunity rather than increasing drug resistance.In vitro activity of antifolate and polymorphism in dihydrofolate reductase of Plasmodium falciparum isolates from the Kenyan coast: emergence of parasites with Ile-164-Leu mutation.Plasmodium falciparum drug resistance in Madagascar: facing the spread of unusual pfdhfr and pfmdr-1 haplotypes and the decrease of dihydroartemisinin susceptibility.Placental malaria among HIV-infected and uninfected women receiving anti-folates in a high transmission area of Uganda.Changing Antimalarial Drug Resistance Patterns Identified by Surveillance at Three Sites in Uganda.Unexpected selections of Plasmodium falciparum polymorphisms in previously treatment-naïve areas after monthly presumptive administration of three different anti-malarial drugs in Liberia 1976-78.Monitoring for multidrug-resistant Plasmodium falciparum isolates and analysis of pyrimethamine resistance evolution in Uige province, Angola.Plasmodium falciparum and dihydrofolate reductase I164L mutations in Africa.Antifolate drug resistance: Novel mutations and haplotype distribution in dhps and dhfr from Northeast India.
P2860
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P2860
Emergence of a dhfr mutation conferring high-level drug resistance in Plasmodium falciparum populations from southwest Uganda.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Emergence of a dhfr mutation c ...... lations from southwest Uganda.
@en
type
label
Emergence of a dhfr mutation c ...... lations from southwest Uganda.
@en
prefLabel
Emergence of a dhfr mutation c ...... lations from southwest Uganda.
@en
P2093
P356
P1476
Emergence of a dhfr mutation c ...... lations from southwest Uganda.
@en
P2093
Caroline Lynch
Hirva Pota
James Tibenderana
John Rwakimari
Jonathan Cox
Richard Pearce
Tarekegn A Abeku
P304
P356
10.1086/587845
P407
P577
2008-06-01T00:00:00Z