Synthesis, LSD1 Inhibitory Activity, and LSD1 Binding Model of Optically Pure Lysine-PCPA Conjugates.

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Computer-aided Molecular Design of Compounds Targeting Histone Modifying Enzymes KDM1 class flavin-dependent protein lysine demethylases Medicinal chemistry insights in the discovery of novel LSD1 inhibitors.TCPs: privileged scaffolds for identifying potent LSD1 inhibitors for cancer therapy.

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P2860

Synthesis, LSD1 Inhibitory Activity, and LSD1 Binding Model of Optically Pure Lysine-PCPA Conjugates.

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2014 nî lūn-bûn

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年學術文章

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2014年學術文章

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2014年學術文章

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name

Synthesis, LSD1 Inhibitory Act ...... y Pure Lysine-PCPA Conjugates.

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type

Item

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Synthesis, LSD1 Inhibitory Act ...... y Pure Lysine-PCPA Conjugates.

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prefLabel

Synthesis, LSD1 Inhibitory Act ...... y Pure Lysine-PCPA Conjugates.

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P1476

Synthesis, LSD1 Inhibitory Act ...... y Pure Lysine-PCPA Conjugates.

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Daisuke Ogasawara

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Takayoshi Suzuki

http://www.w3.org/2001/XMLSchema#string

Tamio Mizukami

http://www.w3.org/2001/XMLSchema#string

Yosuke Ota

http://www.w3.org/2001/XMLSchema#string

P2860

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

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Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine

Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2

Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1

Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy

Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

Multivalent engagement of chromatin modifications by linked binding modules

trans-2-Phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1.

Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction

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e201402002

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scholarly article

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10.5936/CSBJ.201402002

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Yukihiro Itoh

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2014-02-15T00:00:00Z

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261803053

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3995212

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Synthesis, LSD1 Inhibitory Activity, and LSD1 Binding Model of Optically Pure Lysine-PCPA Conjugates.

about

P2860

P2860

Synthesis, LSD1 Inhibitory Activity, and LSD1 Binding Model of Optically Pure Lysine-PCPA Conjugates.

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P1433

P1476

P2093

P2860

P304

P31

P356

P478

P50

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P478

P50

P577

P5875

P698

P932