A Diverse Repertoire of Human Immunoglobulin Variable Genes in a Chicken B Cell Line is Generated by Both Gene Conversion and Somatic Hypermutation.
about
Generation of a highly diverse panel of antagonistic chicken monoclonal antibodies against the GIP receptorAssessing kinetic and epitopic diversity across orthogonal monoclonal antibody generation platformsExpression of heavy chain-only antibodies can support B-cell development in light chain knockout chickens.The transgenic animal platform for biopharmaceutical production.High-efficiency antibody discovery achieved with multiplexed microscopy.Chickens with humanized immunoglobulin genes generate antibodies with high affinity and broad epitope coverage to conserved targets.IgY: a key isotype in antibody evolution.V(D)J Rearrangement Is Dispensable for Producing CDR-H3 Sequence Diversity in a Gene Converting Species.Applications of Gene Editing in Chickens: A New Era Is on the Horizon
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P2860
A Diverse Repertoire of Human Immunoglobulin Variable Genes in a Chicken B Cell Line is Generated by Both Gene Conversion and Somatic Hypermutation.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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name
A Diverse Repertoire of Human ...... ion and Somatic Hypermutation.
@en
type
label
A Diverse Repertoire of Human ...... ion and Somatic Hypermutation.
@en
prefLabel
A Diverse Repertoire of Human ...... ion and Somatic Hypermutation.
@en
P2093
P2860
P356
P1476
A Diverse Repertoire of Human ...... ion and Somatic Hypermutation.
@en
P2093
Benjamin Schusser
Jacob Glanville
Philip A Leighton
William Harriman
P2860
P356
10.3389/FIMMU.2015.00126
P577
2015-03-20T00:00:00Z