MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection
about
Writers, Readers, and Erasers of Histone Ubiquitylation in DNA Double-Strand Break RepairInterplay between Ubiquitin, SUMO, and Poly(ADP-Ribose) in the Cellular Response to Genotoxic StressRole of Deubiquitinating Enzymes in DNA RepairThe multifaceted roles of the HORMA domain in cellular signalingHomologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian CancerInhibition of Topoisomerase (DNA) I (TOP1): DNA Damage Repair and Anticancer TherapyReplication stress in Mammalian cells and its consequences for mitosisA Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds53BP1 and the LINC Complex Promote Microtubule-Dependent DSB Mobility and DNA RepairThe p53-binding protein 1-Tudor-interacting repair regulator complex participates in the DNA damage response.Clinical Application of Poly(ADP-Ribose) Polymerase Inhibitors in High-Grade Serous Ovarian Cancer.DNA double-strand break repair: a tale of pathway choices.Deciphering the BRCA1 Tumor Suppressor Network.Processing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks.Platinum and PARP Inhibitor Resistance Due to Overexpression of MicroRNA-622 in BRCA1-Mutant Ovarian Cancer.Complex interactions between the DNA-damage response and mammalian telomeres.Rev7/Mad2B plays a critical role in the assembly of a functional mitotic spindle.De novo pathogenic variants in CHAMP1 are associated with global developmental delay, intellectual disability, and dysmorphic facial featuresRepair Pathway Choices and Consequences at the Double-Strand BreakMechanism and regulation of DNA end resection in eukaryotesA PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation.Stop pulling my strings - what telomeres taught us about the DNA damage response.PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining.MAD2L2 Promotes Open Chromatin in Embryonic Stem Cells and Derepresses the Dppa3 LocusBiallelic inactivation of REV7 is associated with Fanconi anemia.53BP1 fosters fidelity of homology-directed DNA repair.Genetic Dissection of Cancer Development, Therapy Response, and Resistance in Mouse Models of Breast Cancer.Hypoxia-driven splicing into noncoding isoforms regulates the DNA damage response.Regulatory cross-talk determines the cellular levels of 53BP1 protein, a critical factor in DNA repair.Eukaryotic DNA Polymerases in Homologous Recombination.The control of DNA repair by the cell cycle.Therapeutic targeting and patient selection for cancers with homologous recombination defects.Cell cycle-dependent control of homologous recombination.Ubiquitination and SUMOylation in Telomere Maintenance and Dysfunction.Recent insights into the molecular basis of Fanconi anemia: genes, modifiers, and drivers.TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres.High expression of REV7 is an independent prognostic indicator in patients with diffuse large B-cell lymphoma treated with rituximab.Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy?DNA repair goes hip-hop: SMARCA and CHD chromatin remodellers join the break dance.The role of 53BP1 protein in homology-directed DNA repair: things get a bit complicated.
P2860
Q26742134-16C865CB-E352-4396-9A3A-F5BACCD540BEQ26752447-FC7E3822-A7B0-42F5-8FDC-0C6456F5159BQ26773800-536097CB-525F-4E22-A0AF-43516D2D424DQ26776388-ECE9BEF0-36AB-44CE-8325-65F0A0375553Q26783551-DFBA604C-6909-4993-B500-61322DA480B9Q26796576-E2EE14D4-EA6A-45C3-AA09-5A22E8CB811EQ28087011-508B05A7-3F8E-454E-8C89-EDF8D641B2D7Q28598343-02CF178A-E493-468A-AF7F-3602926F7308Q30673640-BBE4A3BA-3C72-4046-9947-796F71F5D840Q33586561-5B81B86B-EE8D-41EF-A4DF-B93EDC6AEBFFQ34520145-B76C7559-E6B6-4126-9A70-9FFB0C65AC49Q34528005-9A9FC763-DF76-4B56-B726-7F6D2CD8E4D8Q35859458-96FD811E-E079-4CEE-BF26-883840273E6AQ36299151-9A9C95D7-BBCD-4A72-80CD-D4F26695502DQ36515439-51025DC8-EF3D-4F54-8CC3-0D1C1F0F55FDQ36539673-B24AFD26-7352-494B-830B-D644DFAAD953Q36781066-5F0DC791-8167-4309-8CD9-B6B666042B89Q36849253-9AC595E6-A60C-4BD1-ACB0-61005C22AC67Q36888291-7D001680-C231-4D25-8ACE-2B483D9362C2Q37118849-D48659B0-CCB4-4BE4-9326-B4BC01492FF1Q37669871-4826AEFE-4692-476D-9374-7234685E170FQ37742751-85DD4C57-DE8A-481B-8321-943C9A129417Q38655716-37C2B479-E0D6-454C-B121-300EEBBD8CABQ38711158-1C2505E1-BC2F-44D7-BF49-23C02292926CQ38753157-52F477E3-694C-4920-B8FF-4CD4407AE1EDQ38761656-985DAD0E-D670-43CD-828E-9ED7375E0D1BQ38798405-BF766EF7-4295-4789-95B2-10796A01D6BFQ38799220-CFD13366-5FEE-4B41-BD8D-229F91599BE7Q38932240-96B65235-48D1-4CEB-9DE2-EBF061D3A936Q39022234-9D1BE0DC-2F01-4762-8341-DD9FAFC3C80DQ39051119-85063615-7003-422E-923F-39442DB3BF25Q39251572-A1339209-FC51-4C44-B240-C8631763FFA9Q39328632-A24C90B8-E53F-4128-93C2-802059C9090EQ39355466-CA293188-F2B2-4658-AFB3-D230B9228F4AQ39385071-C7BEA546-6A71-4B3F-9E31-F8527E629EABQ40096779-88658DA8-1275-4D59-922F-9904CE7F05AFQ41245405-5DDCBCE2-E04B-4717-967B-E110AE0A4195Q41443583-96AB7508-D397-4407-AFA3-6F4BFD5B833BQ41568111-E9CDE4E1-5228-42EE-8D76-3EEBD346FB2DQ42031570-E12C6583-D98E-464C-9BFE-1A85230AD73A
P2860
MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection
@en
type
label
MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection
@en
prefLabel
MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection
@en
P2093
P2860
P356
P1433
P1476
MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection
@en
P2093
Alexandre Orthwein
Brigitte A Wevers
Daniel Durocher
Jaco van der Torre
Marieke H Peuscher
Nathalie Moatti
Vera Boersma
P2860
P2888
P304
P356
10.1038/NATURE14216
P407
P577
2015-03-23T00:00:00Z
P5875
P6179
1012247031