The thymidine-dependent small-colony-variant phenotype is associated with hypermutability and antibiotic resistance in clinical Staphylococcus aureus isolates.
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Phenotypic and Genotypic Characteristics of Small Colony Variants and Their Role in Chronic InfectionAntibiotic activity against small-colony variants of Staphylococcus aureus: review of in vitro, animal and clinical data.Adaptive evolution of Staphylococcus aureus during chronic endobronchial infection of a cystic fibrosis patient.Pharmacokinetics and pharmacodynamics of aerosolized antibacterial agents in chronically infected cystic fibrosis patients.Clinical significance of microbial infection and adaptation in cystic fibrosis.PBP2a mutations causing high-level Ceftaroline resistance in clinical methicillin-resistant Staphylococcus aureus isolates.Intra- and extracellular activities of dicloxacillin and linezolid against a clinical Staphylococcus aureus strain with a small-colony-variant phenotype in an in vitro model of THP-1 macrophages and an in vivo mouse peritonitis model.Impact of ciprofloxacin exposure on Staphylococcus aureus genomic alterations linked with emergence of rifampin resistance.The genetic basis of Escherichia coli pathoadaptation to macrophages.Thymidine auxotrophic Staphylococcus aureus small-colony variant endocarditis and left ventricular assist device infection.Activation of the SOS response increases the frequency of small colony variantsRapid Acquisition of Linezolid Resistance in Methicillin-Resistant Staphylococcus aureus: Role of Hypermutation and Homologous Recombination.Thymidine-Dependent Staphylococcus aureus Small-Colony Variants Are Induced by Trimethoprim-Sulfamethoxazole (SXT) and Have Increased Fitness during SXT Challenge.Evolution in fast forward: a potential role for mutators in accelerating Staphylococcus aureus pathoadaptation.Identification of the genetic basis for clinical menadione-auxotrophic small-colony variant isolates of Staphylococcus aureus.Thymidine-dependent Staphylococcus aureus small-colony variants: human pathogens that are relevant not only in cases of cystic fibrosis lung disease.Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenoIntracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: study of antibiotic combinationsHypermutation and stress adaptation in bacteria.Antibiotrophs: The complexity of antibiotic-subsisting and antibiotic-resistant microorganisms.Infection in cystic fibrosis: impact of the environment and climate.Altered Competitive Fitness, Antimicrobial Susceptibility, and Cellular Morphology in a Triclosan-Induced Small-Colony Variant of Staphylococcus aureus.Phenotype switching is a natural consequence of Staphylococcus aureus replication.Infection prevention and control guideline for cystic fibrosis: 2013 update.Role of mutations in dihydrofolate reductase DfrA (Rv2763c) and thymidylate synthase ThyA (Rv2764c) in Mycobacterium tuberculosis drug resistance.Lack of association of small-colony-variant Staphylococcus aureus strains with long-term use of azithromycin in patients with cystic fibrosis.Mutability in Pseudomonas viridiflava as a programmed balance between antibiotic resistance and pathogenicity.Antimicrobial susceptibility and molecular typing of MRSA in cystic fibrosis.
P2860
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P2860
The thymidine-dependent small-colony-variant phenotype is associated with hypermutability and antibiotic resistance in clinical Staphylococcus aureus isolates.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
The thymidine-dependent small- ...... taphylococcus aureus isolates.
@en
type
label
The thymidine-dependent small- ...... taphylococcus aureus isolates.
@en
prefLabel
The thymidine-dependent small- ...... taphylococcus aureus isolates.
@en
P2093
P2860
P356
P1476
The thymidine-dependent small- ...... taphylococcus aureus isolates.
@en
P2093
Johannes Zander
Peter Kraiczy
Silke Besier
Thomas A Wichelhaus
Volker Brade
P2860
P304
P356
10.1128/AAC.01395-07
P407
P577
2008-03-31T00:00:00Z