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Antibiotic activity against small-colony variants of Staphylococcus aureus: review of in vitro, animal and clinical data.Emergence of respiratory Streptococcus agalactiae isolates in cystic fibrosis patients.Staphylococcus aureus panton-valentine leukocidin is a very potent cytotoxic factor for human neutrophils.Staphylococcus aureus Small Colony Variants (SCVs): a road map for the metabolic pathways involved in persistent infectionsInactivation of thyA in Staphylococcus aureus attenuates virulence and has a strong impact on metabolism and virulence gene expression.Two diarylurea electron transport inhibitors reduce Staphylococcus aureus hemolytic activity and protect cultured endothelial cells from lysis.Retrospective analysis of antimicrobial resistance and bacterial spectrum of infection in Gabon, Central AfricaPopulation dynamics of persistent Staphylococcus aureus isolated from the airways of cystic fibrosis patients during a 6-year prospective study.Nasal Staphylococcus aureus carriage is not a risk factor for lower-airway infection in young cystic fibrosis patientsFactors Associated with Worse Lung Function in Cystic Fibrosis Patients with Persistent Staphylococcus aureus.Dynamic in vivo mutations within the ica operon during persistence of Staphylococcus aureus in the airways of cystic fibrosis patients.Thymidine-Dependent Staphylococcus aureus Small-Colony Variants Are Induced by Trimethoprim-Sulfamethoxazole (SXT) and Have Increased Fitness during SXT Challenge.Small colony variants: a pathogenic form of bacteria that facilitates persistent and recurrent infections.Chromosomally and Extrachromosomally Mediated High-Level Gentamicin Resistance in Streptococcus agalactiaeClinical Significance and Pathogenesis of Staphylococcal Small Colony Variants in Persistent Infections.Predictive diagnostics for Escherichia coli infections based on the clonal association of antimicrobial resistance and clinical outcomeCharacterization of clinical Enterococcus faecalis small-colony variantsThe epidemic of extended-spectrum-β-lactamase-producing Escherichia coli ST131 is driven by a single highly pathogenic subclone, H30-Rx.Non-spa-typeable clinical Staphylococcus aureus strains are naturally occurring protein A mutants.Impact of Staphylococcus aureus on the pathogenesis of chronic cystic fibrosis lung disease.Small colony variants (SCVs) of Staphylococcus aureus--a bacterial survival strategy.Assessment of microbiological diagnostic procedures for respiratory specimens from cystic fibrosis patients in German laboratories by use of a questionnaire.The thymidine-dependent small-colony-variant phenotype is associated with hypermutability and antibiotic resistance in clinical Staphylococcus aureus isolates.Intracellular forms of menadione-dependent small-colony variants of methicillin-resistant Staphylococcus aureus are hypersusceptible to β-lactams in a THP-1 cell model due to cooperation between vacuolar acidic pH and oxidant species.The length of the Staphylococcus aureus protein A polymorphic region regulates inflammation: impact on acute and chronic infection.Staphylococcus aureus RN6390 replicates and induces apoptosis in a pulmonary epithelial cell line.Thymidine-dependent small-colony variants of Staphylococcus aureus exhibit gross morphological and ultrastructural changes consistent with impaired cell separation.Lack of Sphingosine Causes Susceptibility to Pulmonary Staphylococcus Aureus Infections in Cystic Fibrosis.agr-dependent bacterial interference has no impact on long-term colonization of Staphylococcus aureus during persistent airway infection of cystic fibrosis patients.High-level resistance to meropenem in clinical isolates of Pseudomonas aeruginosa in the absence of carbapenemases: role of active efflux and porin alterations.Antimicrobial Susceptibility of Pseudomonas aeruginosa Isolated from Cystic Fibrosis Patients in Northern Europe.Variation of the polymorphic region X of the protein A gene during persistent airway infection of cystic fibrosis patients reflects two independent mechanisms of genetic change in Staphylococcus aureus.The clinical impact of livestock-associated methicillin-resistant Staphylococcus aureus of the clonal complex 398 for humans.Increased Prevalence and Resistance of Important Pathogens Recovered from Respiratory Specimens of Cystic Fibrosis Patients During a Decade.Microarray-based identification of human antibodies against Staphylococcus aureus antigens.Transcriptional adaptations during long-term persistence of Staphylococcus aureus in the airways of a cystic fibrosis patient.Staphylococcus aureus small colony variants show common metabolic features in central metabolism irrespective of the underlying auxotrophism.Evaluation of two chromogenic agar media for recovery and identification of Staphylococcus aureus small-colony variants.In vivo mutations of thymidylate synthase (encoded by thyA) are responsible for thymidine dependency in clinical small-colony variants of Staphylococcus aureus.Thymidine-dependent Staphylococcus aureus small-colony variants are associated with extensive alterations in regulator and virulence gene expression profiles.
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Barbara C. Kahl
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Barbara C. Kahl
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Barbara C. Kahl
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Barbara C. Kahl
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Barbara C. Kahl
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Barbara C. Kahl
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Barbara C. Kahl
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Barbara C. Kahl
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Barbara C. Kahl
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Barbara C. Kahl
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Barbara C. Kahl
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Barbara C. Kahl
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Barbara C. Kahl
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Barbara C. Kahl
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0000-0001-5155-3383