A2A adenosine receptor antagonists to weaken the hypoxia-HIF-1α driven immunosuppression and improve immunotherapies of cancer.
about
Fragment optimization for GPCRs by molecular dynamics free energy calculations: Probing druggable subpockets of the A 2A adenosine receptor binding site.Safety issues of compounds acting on adenosinergic signalling.Pathological overproduction: the bad side of adenosine.Fasting inhibits colorectal cancer growth by reducing M2 polarization of tumor-associated macrophages.Metformin-induced reduction of CD39 and CD73 blocks myeloid-derived suppressor cell activity in patients with ovarian cancer.Bitopic fluorescent antagonists of the A2A adenosine receptor based on pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine functionalized congeners.Breathing New Life Into Hypoxia-Targeted Therapies for Non-Small Cell Lung Cancer.Cutting Edge: Adenosine A2a Receptor Signals Inhibit Germinal Center T Follicular Helper Cell Differentiation during the Primary Response to Vaccination.Adenosine metabolism, immunity and joint health.Immunological Approaches Towards Cancer and Inflammation: A Cross Talk.A targeted immunotherapy approach for HER2/neu transformed tumors by coupling an engineered effector domain with interferon-γ.Treatment for Patients With Malignant Pheochromocytomas and Paragangliomas: A Perspective From the Hallmarks of Cancer.Cytokine-Induced Killer Cells Express CD39, CD38, CD203a, CD73 Ectoenzymes and P1 Adenosinergic Receptors.Adenosine A2A Receptor Antagonists in Neurodegenerative Diseases: Huge Potential and Huge Challenges.Immune oncology, immune responsiveness and the theory of everything.Overcoming tumor hypoxia as a barrier to radiotherapy, chemotherapy and immunotherapy in cancer treatment
P2860
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P2860
A2A adenosine receptor antagonists to weaken the hypoxia-HIF-1α driven immunosuppression and improve immunotherapies of cancer.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
A2A adenosine receptor antagon ...... ove immunotherapies of cancer.
@en
type
label
A2A adenosine receptor antagon ...... ove immunotherapies of cancer.
@en
prefLabel
A2A adenosine receptor antagon ...... ove immunotherapies of cancer.
@en
P2860
P1476
A2A adenosine receptor antagon ...... ove immunotherapies of cancer.
@en
P2093
Michail Sitkovsky
Stephen M Hatfield
P2860
P356
10.1016/J.COPH.2016.06.009
P577
2016-07-15T00:00:00Z