CD73 on tumor cells impairs antitumor T-cell responses: a novel mechanism of tumor-induced immune suppression
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A Metabolic Immune Checkpoint: Adenosine in Tumor MicroenvironmentCD73 and CD39 ectonucleotidases in T cell differentiation: Beyond immunosuppressionCD73-generated adenosine: orchestrating the tumor-stroma interplay to promote cancer growthImmune modulation of the tumor microenvironment for enhancing cancer immunotherapyEctonucleotidases in tumor cells and tumor-associated immune cells: an overviewCD73 expression is dynamically regulated in the germinal center and bone marrow plasma cells are diminished in its absenceThe Multifaceted Roles Neutrophils Play in the Tumor MicroenvironmentBioorthogonal labeling cell-surface proteins expressed in pancreatic cancer cells to identify potential diagnostic/therapeutic biomarkersAdenosine receptors as drug targets--what are the challenges?Immunological alterations mediated by adenosine during host-microbial interactionsMuch ado about adenosine: adenosine synthesis and function in regulatory T cell biology.Inosine Released from Dying or Dead Cells Stimulates Cell Proliferation via Adenosine Receptors.A Novel Antagonist of the Immune Checkpoint Protein Adenosine A2a Receptor Restores Tumor-Infiltrating Lymphocyte Activity in the Context of the Tumor Microenvironment.Extracellular adenosine-mediated modulation of regulatory T cells.Treatment with a rho kinase inhibitor improves survival from graft-versus-host disease in mice after MHC-haploidentical hematopoietic cell transplantation.The roles of CD73 in cancerCellular function and molecular structure of ecto-nucleotidases.NTPDase3 and ecto-5'-nucleotidase/CD73 are differentially expressed during mouse bladder cancer progression.Roles of the adenosine receptor and CD73 in the regulatory effect of γδ T cells.Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacySystemic oxygenation weakens the hypoxia and hypoxia inducible factor 1α-dependent and extracellular adenosine-mediated tumor protection.Graft-versus-host disease is enhanced by selective CD73 blockade in miceVascular CD39/ENTPD1 directly promotes tumor cell growth by scavenging extracellular adenosine triphosphate.P2X7 integrates PI3K/AKT and AMPK-PRAS40-mTOR signaling pathways to mediate tumor cell death.Regulatory T cells negatively affect IL-2 production of effector T cells through CD39/adenosine pathway in HIV infectionCD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in miceHost miR155 promotes tumor growth through a myeloid-derived suppressor cell-dependent mechanism.Hostile, hypoxia-A2-adenosinergic tumor biology as the next barrier to overcome for tumor immunologistsImmunotherapy for ovarian cancer.Organocatalytic High Enantioselective Synthesis of β-Formyl-α-hydroxyphosphonates.Adenosinergic regulation of the expansion and immunosuppressive activity of CD11b+Gr1+ cells.Immune microenvironments in solid tumors: new targets for therapy.An A2B Adenosine Receptor Agonist Promotes Th17 Autoimmune Responses in Experimental Autoimmune Uveitis (EAU) via Dendritic Cell Activation.Ecto-5'-nucleotidase expression is associated with the progression of renal cell carcinoma.Fibroblast-Derived Extracellular Matrices: An Alternative Cell Culture System That Increases Metastatic Cellular PropertiesCD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell deathCD73 Expressed on γδ T Cells Shapes Their Regulatory Effect in Experimental Autoimmune UveitisDeficiency of CD73/ecto-5'-nucleotidase in mice enhances acute graft-versus-host diseaseImmune escape to PD-L1/PD-1 blockade: seven steps to success (or failure).CD73 promotes tumor growth and metastasis
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P2860
CD73 on tumor cells impairs antitumor T-cell responses: a novel mechanism of tumor-induced immune suppression
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年学术文章
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2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
CD73 on tumor cells impairs an ...... mor-induced immune suppression
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CD73 on tumor cells impairs an ...... mor-induced immune suppression
@en
CD73 on tumor cells impairs an ...... or-induced immune suppression.
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CD73 on tumor cells impairs an ...... mor-induced immune suppression
@ast
CD73 on tumor cells impairs an ...... mor-induced immune suppression
@en
CD73 on tumor cells impairs an ...... or-induced immune suppression.
@nl
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CD73 on tumor cells impairs an ...... mor-induced immune suppression
@ast
CD73 on tumor cells impairs an ...... mor-induced immune suppression
@en
CD73 on tumor cells impairs an ...... or-induced immune suppression.
@nl
P2093
P2860
P1433
P1476
CD73 on tumor cells impairs an ...... mor-induced immune suppression
@en
P2093
Benjamin J Daniel
Dachuan Jin
Linda F Thompson
Tahiro Shin
Tyler J Curiel
P2860
P304
P356
10.1158/0008-5472.CAN-09-3109
P407
P577
2010-02-23T00:00:00Z