Allotopic mRNA localization to the mitochondrial surface rescues respiratory chain defects in fibroblasts harboring mitochondrial DNA mutations affecting complex I or v subunits.
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Allotopic expression of mitochondrial-encoded genes in mammals: achieved goal, undemonstrated mechanism or impossible task?Mitochondrial geneticsIs there treatment for Leber hereditary optic neuropathy?A single mutation in the first transmembrane domain of yeast COX2 enables its allotopic expression.Differential targeting of VDAC3 mRNA isoforms influences mitochondria morphologyRespiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells.Leber's Hereditary Optic Neuropathy-Gene Therapy: From Benchtop to Bedside.Nuclear expression of mitochondrial ND4 leads to the protein assembling in complex I and prevents optic atrophy and visual loss.Localized translation near the mitochondrial outer membrane: An update.Efficacy and Safety of rAAV2-ND4 Treatment for Leber's Hereditary Optic NeuropathyOptimized allotopic expression of the human mitochondrial ND4 prevents blindness in a rat model of mitochondrial dysfunction.Phosphorylated neurofilament heavy chain is a marker of neurodegeneration in Leber hereditary optic neuropathy (LHON)Progress and prospects: gene therapy for mitochondrial DNA disease.Molecular diagnostics and mitochondrial dysfunction: a future perspective.The approaches for manipulating mitochondrial proteomeMitochondrial medicine: to a new era of gene therapy for mitochondrial DNA mutations.Treatment of hereditary optic neuropathies.Leber Hereditary Optic Neuropathy: Exemplar of an mtDNA Disease.The Progress of Gene Therapy for Leber`s Optic Hereditary Neuropathy.Mitochondrial versus nuclear gene expression and membrane protein assembly: The case of subunit 2 of yeast cytochrome c oxidase.Patient-derived lymphoblastoid cell lines harboring mitochondrial DNA mutations as tool for small molecule drug discovery.
P2860
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P2860
Allotopic mRNA localization to the mitochondrial surface rescues respiratory chain defects in fibroblasts harboring mitochondrial DNA mutations affecting complex I or v subunits.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Allotopic mRNA localization to ...... cting complex I or v subunits.
@en
type
label
Allotopic mRNA localization to ...... cting complex I or v subunits.
@en
prefLabel
Allotopic mRNA localization to ...... cting complex I or v subunits.
@en
P2093
P356
P1476
Allotopic mRNA localization to ...... cting complex I or v subunits.
@en
P2093
Marisol Corral-Debrinski
Paule Bénit
Pierre Rustin
Sami Ellouze
Sébastien Augustin
Valérie Forster
Valérie Kaltimbacher
P304
P356
10.1089/REJ.2006.0526
P407
P577
2007-06-01T00:00:00Z