Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice.
about
The Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and RepairUbiquitylation, neddylation and the DNA damage responseNeddylation promotes ubiquitylation and release of Ku from DNA-damage sites.A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection.Repair Pathway Choices and Consequences at the Double-Strand BreakThe transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression.Genetic and biochemical evidences reveal novel insights into the mechanism underlying Saccharomyces cerevisiae Sae2-mediated abrogation of DNA replication stress.Targeting Mcl-1 enhances DNA replication stress sensitivity to cancer therapy.NEDDylation antagonizes ubiquitination of proliferating cell nuclear antigen and regulates the recruitment of polymerase η in response to oxidative DNA damage.Protein neddylation and its alterations in human cancers for targeted therapy.How cells ensure correct repair of DNA double-strand breaks.Targeting repair pathways with small molecules increases precise genome editing in pluripotent stem cells.
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Q26782011-5266196D-10CA-4699-9056-EA58B205743DQ28087342-F1E6C0D9-0351-471D-9B75-57E4DBFD575AQ34474077-AF6BD731-DB80-4207-A3EB-58012AAF6B0FQ36098301-03C2201A-62C8-4E6D-9D9F-C574A4E41B04Q36888291-4EBD5EA3-BB77-4FD5-A3AA-898AB277C0E4Q38798176-4636D999-2DA3-4F7F-A08D-0FB164081165Q39102719-54D8B6EA-EBBA-473C-BE6D-EAA0492AFCD7Q47308626-C979E636-F462-4A13-9881-D9F34DC74626Q47918567-ECBCB843-C231-48EA-91D0-8C5300C26EFBQ48538797-163010EE-334C-4B79-A06C-6A41BC8DEF5FQ50134088-52B098CE-4AD9-4E05-B693-7EAC66A14E6DQ55168127-C95525F1-0232-4D89-BF67-1F51FF784C15
P2860
Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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2015年學術文章
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2015年學術文章
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name
Neddylation inhibits CtIP-medi ...... d break repair pathway choice.
@en
type
label
Neddylation inhibits CtIP-medi ...... d break repair pathway choice.
@en
prefLabel
Neddylation inhibits CtIP-medi ...... d break repair pathway choice.
@en
P2093
P2860
P50
P356
P1476
Neddylation inhibits CtIP-medi ...... d break repair pathway choice.
@en
P2093
Cristina Cepeda-García
María Jesús Fernández-Ávila
Sonia Jimeno
P2860
P304
P356
10.1093/NAR/GKU1384
P407
P577
2015-01-07T00:00:00Z