Comparing signaling networks between normal and transformed hepatocytes using discrete logical models.
about
SBML qualitative models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and toolsSTL-based analysis of TRAIL-induced apoptosis challenges the notion of type I/type II cell line classificationInferring causal molecular networks: empirical assessment through a community-based effortNetwork reconstruction based on proteomic data and prior knowledge of protein connectivity using graph theoryModels of signalling networks - what cell biologists can gain from them and give to themCellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms.A reverse-engineering approach to dissect post-translational modulators of transcription factor's activity from transcriptional dataNonparametric simulation of signal transduction networks with semi-synchronized updateContinuous time Boolean modeling for biological signaling: application of Gillespie algorithm.Perturbation biology nominates upstream-downstream drug combinations in RAF inhibitor resistant melanoma cells.Central role for MCP-1/CCL2 in injury-induced inflammation revealed by in vitro, in silico, and clinical studiesNetwork based elucidation of drug response: from modulators to targets.Angiogenic activity of breast cancer patients' monocytes reverted by combined use of systems modeling and experimental approachesCell fate reprogramming by control of intracellular network dynamics.Disentangling the Complexity of HGF Signaling by Combining Qualitative and Quantitative Modeling.Logic-Based and Cellular Pharmacodynamic Modeling of Bortezomib Responses in U266 Human Myeloma Cells.Qualitative Dynamical Modelling Can Formally Explain Mesoderm Specification and Predict Novel Developmental PhenotypesNetwork modelling reveals the mechanism underlying colitis-associated colon cancer and identifies novel combinatorial anti-cancer targets.Breaking resistance of pancreatic cancer cells to an attenuated vesicular stomatitis virus through a novel activity of IKK inhibitor TPCA-1Investigation into the effects of antioxidant-rich extract of Tamarindus indica leaf on antioxidant enzyme activities, oxidative stress and gene expression profiles in HepG2 cellsA dual array-based approach to assess the abundance and posttranslational modification state of signaling proteinsA Six-Stage Workflow for Robust Application of Systems Pharmacology.Inflammatory mediators increase SUMOylation of retinoid X receptor α in a c-Jun N-terminal kinase-dependent manner in human hepatocellular carcinoma cells.Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Advanced systems biology methods in drug discovery and translational biomedicineAntioxidant-rich leaf extract of Barringtonia racemosa significantly alters the in vitro expression of genes encoding enzymes that are involved in methylglyoxal degradation IIIContext Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling.Network quantification of EGFR signaling unveils potential for targeted combination therapy.Predictive mathematical models of cancer signalling pathways.Network pharmacology strategies toward multi-target anticancer therapies: from computational models to experimental design principles.Cancer Systems Biology: a peek into the future of patient care?Signaling networks in MS: a systems-based approach to developing new pharmacological therapies.Role of phosphoproteomics in the development of personalized cancer therapies.Logic Modeling in Quantitative Systems Pharmacology.Modeling the Attractor Landscape of Disease Progression: a Network-Based Approach.Human hepatocytes derived from pluripotent stem cells: a promising cell model for drug hepatotoxicity screening.Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis.Inferring the Effects of Honokiol on the Notch Signaling Pathway in SW480 Colon Cancer Cells.Establishment of a human 3D lung cancer model based on a biological tissue matrix combined with a Boolean in silico model.The recurrent architecture of tumour initiation, progression and drug sensitivity.
P2860
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P2860
Comparing signaling networks between normal and transformed hepatocytes using discrete logical models.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Comparing signaling networks b ...... using discrete logical models.
@en
type
label
Comparing signaling networks b ...... using discrete logical models.
@en
prefLabel
Comparing signaling networks b ...... using discrete logical models.
@en
P2093
P2860
P50
P1433
P1476
Comparing signaling networks b ...... using discrete logical models.
@en
P2093
Leonidas G Alexopoulos
Melody K Morris
Mingsheng Zhang
P2860
P304
P356
10.1158/0008-5472.CAN-10-4453
P407
P577
2011-07-08T00:00:00Z