Multiple compound-related adverse properties contribute to liver injury caused by endothelin receptor antagonists.
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Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation PlansSandwich-Cultured Hepatocytes as a Tool to Study Drug Disposition and Drug-Induced Liver Injury.Human biology-based drug safety evaluation: scientific rationale, current status and future challenges.The Promise of New Technologies to Reduce, Refine, or Replace Animal Use while Reducing Risks of Drug Induced Liver Injury in Pharmaceutical Development.In Silico Modeling for the Prediction of Dose and Pathway-Related Adverse Effects in Humans From In Vitro Repeated-Dose Studies.Quantification of Drug-Induced Inhibition of Canalicular Cholyl-l-Lysyl-Fluorescein Excretion From Hepatocytes by High Content Cell Imaging.Selective endothelin A receptor antagonism with sitaxentan reduces neointimal lesion size in a mouse model of intraluminal injuryUtility of spherical human liver microtissues for prediction of clinical drug-induced liver injury.Safety and Ergogenic Properties of Combined Aminophylline and Ambrisentan in Hypoxia.Prediction of Drug-Induced Hepatotoxicity Using Long-Term Stable Primary Hepatic 3D Spheroid Cultures in Chemically Defined Conditions.Can BSEP Inhibition Testing In Drug Discovery And Development Reduce Liver Injury Risk? - An International Transporter Consortium Perspective
P2860
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P2860
Multiple compound-related adverse properties contribute to liver injury caused by endothelin receptor antagonists.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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name
Multiple compound-related adve ...... dothelin receptor antagonists.
@en
type
label
Multiple compound-related adve ...... dothelin receptor antagonists.
@en
prefLabel
Multiple compound-related adve ...... dothelin receptor antagonists.
@en
P2093
P50
P356
P1476
Multiple compound-related adve ...... dothelin receptor antagonists.
@en
P2093
Alison J Foster
Jonas Bergare
Julie A Eakins
Linda C Andersson
Marie Elebring
Martin Billger
Richard A Thompson
P304
P356
10.1124/JPET.114.220491
P407
P577
2014-12-02T00:00:00Z