Inhibition of DYRK1A and GSK3B induces human β-cell proliferation. - Wikidata - awgldk - TriplyDB

Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.

Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.

http://www.wikidata.org/entity/Q38950360

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Selective inhibition of the kinase DYRK1A by targeting its folding process Direct effect of glucocorticoids on glucose-activated adult rat β-cells increases their cell number and their functional mass for transplantation.The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets.Inhibition of DYRK1A Stimulates Human β-Cell Proliferation Replicative capacity of β-cells and type 1 diabetes.A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation.Pancreas-Specific Delivery of β-Cell Proliferating Small Molecules.New Insights into Diabetes Cell Therapy.Single-Cell Transcriptomics of the Human Endocrine Pancreas.Novel factors modulating human β-cell proliferation.Advances in β cell replacement and regeneration strategies for treating diabetes Systematic single-cell analysis provides new insights into heterogeneity and plasticity of the pancreas.Interrogating islets in health and disease with single-cell technologies Single-Cell Mass Cytometry Analysis of the Human Endocrine Pancreas.Inhibition of DYRK1A disrupts neural lineage specification in human pluripotent stem cells Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas.The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates.Signals in the pancreatic islet microenvironment influence β-cell proliferation.Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors: a survey of recent patent literature.Pancreatic β Cell Regeneration as a Possible Therapy for Diabetes.Regenerative medicine and cell-based approaches to restore pancreatic function.(Re)generating Human Beta Cells: Status, Pitfalls, and Perspectives.Down Syndrome-Associated Diabetes Is Not Due To a Congenital Deficiency in β Cells.Canine leishmaniasis: Genome-wide analysis and antibody response to Lutzomyia longipalpis saliva.Inhibition of TBK1/IKKε Promotes Regeneration of Pancreatic β-cells Pancreas regeneration

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Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.

http://www.wikidata.org/entity/Q38950360

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

@zh

2015年论文

@zh-cn

name

Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.

@en

type

label

Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.

@en

prefLabel

Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.

@en

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Nature Communications

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Inhibition of DYRK1A and GSK3B induces human β-cell proliferation

@en

P2093

Andrew F Powers

http://www.w3.org/2001/XMLSchema#string

Ann E Herman

http://www.w3.org/2001/XMLSchema#string

Anwesh Kamireddy

http://www.w3.org/2001/XMLSchema#string

Austin Swafford

http://www.w3.org/2001/XMLSchema#string

Badry Bursalaya

http://www.w3.org/2001/XMLSchema#string

Bernhard J Hering

http://www.w3.org/2001/XMLSchema#string

Brandon Taylor

http://www.w3.org/2001/XMLSchema#string

Bryan Laffitte

http://www.w3.org/2001/XMLSchema#string

Carolina N Turk

http://www.w3.org/2001/XMLSchema#string

Christophe M Filippi

http://www.w3.org/2001/XMLSchema#string

P2860

Induction of human beta-cell proliferation and engraftment using a single G1/S regulatory molecule, cdk6

A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT

Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

RETRACTED: Betatrophin: a hormone that controls pancreatic β cell proliferation

Discovery of novel potent and highly selective glycogen synthase kinase-3β (GSK3β) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Regulation of DNA double-strand break repair pathway choice

Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders

DYRK1A enhances the mitogen-activated protein kinase cascade in PC12 cells by forming a complex with Ras, B-Raf, and MEK1.

In vitro proliferation of adult human beta-cells

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8372

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scholarly article

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10.1038/NCOMMS9372

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6

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Michael DiDonato

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2015-10-26T00:00:00Z

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283261964

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1030123628

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26496802

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4639830

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