A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair
about
Spartan/C1orf124 is important to prevent UV-induced mutagenesisFAN1 activity on asymmetric repair intermediates is mediated by an atypical monomeric virus-type replication-repair nuclease domainCtIP is required to initiate replication-dependent interstrand crosslink repairFAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathwayFanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repairDNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1Spartan/C1orf124, a reader of PCNA ubiquitylation and a regulator of UV-induced DNA damage responseA ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair networkZRANB3 is a structure-specific ATP-dependent endonuclease involved in replication stress responseDynamics of DNA damage response proteins at DNA breaks: a focus on protein modificationsMolecular pathogenesis and clinical management of Fanconi anemiaMutations of the SLX4 gene in Fanconi anemiaFunctions of Ubiquitin and SUMO in DNA Replication and Replication StressCellular response to DNA interstrand crosslinks: the Fanconi anemia pathwayRole of Deubiquitinating Enzymes in DNA RepairInhibition of Topoisomerase (DNA) I (TOP1): DNA Damage Repair and Anticancer TherapyExploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer TherapyThe Fanconi anemia pathway and DNA interstrand cross-link repairRINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesisMechanism and regulation of incisions during DNA interstrand cross-link repairPathways for repairing and tolerating the spectrum of oxidative DNA lesionsDiseases associated with defective responses to DNA damageStructure of the FANCI-FANCD2 Complex: Insights into the Fanconi Anemia DNA Repair PathwayThe Fanconi anemia associated protein FAAP24 uses two substrate specific binding surfaces for DNA recognitionThe structure of the FANCM–MHF complex reveals physical features for functional assemblyStructure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage responsePostreplicative mismatch repair.The DNA Damage Response: Making It Safe to Play with KnivesMte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance.Engagement of DYRK2 in proper control for cell divisionUbiquitylation, neddylation and the DNA damage responseEXD2 promotes homologous recombination by facilitating DNA end resectionXPF-ERCC1 acts in Unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP/SLX4Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instabilityFanconi anaemia and the repair of Watson and Crick DNA crosslinksAdvances in understanding the complex mechanisms of DNA interstrand cross-link repairCrystal structure of a Fanconi anemia-associated nuclease homolog bound to 5' flap DNA: basis of interstrand cross-link repair by FAN1.How to link ontologies and protein-protein interactions to literature: text-mining approaches and the BioCreative experienceExpanded roles of the Fanconi anemia pathway in preserving genomic stabilityThe MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination.
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P2860
A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A genetic screen identifies FA ...... A interstrand crosslink repair
@ast
A genetic screen identifies FA ...... A interstrand crosslink repair
@en
A genetic screen identifies FA ...... A interstrand crosslink repair
@en-gb
A genetic screen identifies FA ...... A interstrand crosslink repair
@nl
type
label
A genetic screen identifies FA ...... A interstrand crosslink repair
@ast
A genetic screen identifies FA ...... A interstrand crosslink repair
@en
A genetic screen identifies FA ...... A interstrand crosslink repair
@en-gb
A genetic screen identifies FA ...... A interstrand crosslink repair
@nl
prefLabel
A genetic screen identifies FA ...... A interstrand crosslink repair
@ast
A genetic screen identifies FA ...... A interstrand crosslink repair
@en
A genetic screen identifies FA ...... A interstrand crosslink repair
@en-gb
A genetic screen identifies FA ...... A interstrand crosslink repair
@nl
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A genetic screen identifies FA ...... A interstrand crosslink repair
@en
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Alan B Clark
Francis P Lach
J Wade Harper
Mathew E Sowa
Michael Schlabach
Monica P Colaiácovo
Rohini Desetty
Thomas A Kunkel
P2860
P3181
P356
10.1016/J.MOLCEL.2010.06.023
P407
P577
2010-07-09T00:00:00Z