Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase.
about
A wolf in sheep's clothing: SV40 co-opts host genome maintenance proteins to replicate viral DNADNA replication at the single-molecule levelThe Eukaryotic Replisome Goes Under the MicroscopeInterplay between Fanconi anemia and homologous recombination pathways in genome integrityArchaeal MCM Proteins as an Analog for the Eukaryotic Mcm2-7 Helicase to Reveal Essential Features of Structure and FunctionMechanisms for initiating cellular DNA replicationClose encounters for the first time: Helicase interactions with DNA damagePeaks cloaked in the mist: the landscape of mammalian replication originsRescuing stalled or damaged replication forksMechanism and regulation of incisions during DNA interstrand cross-link repairThe minichromosome maintenance replicative helicaseLoading and activation of DNA replicative helicases: the key step of initiation of DNA replicationNew insights into replisome fluidity during chromosome replicationStructure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocationThe architecture of a eukaryotic replisome.Cryo-EM structures of the eukaryotic replicative helicase bound to a translocation substrate.Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topologyA conserved MCM single-stranded DNA binding element is essential for replication initiationStructure of the eukaryotic MCM complex at 3.8 ÅThe replication initiation protein Sld2 regulates helicase assembly.Mcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation.Cdc45 protein-single-stranded DNA interaction is important for stalling the helicase during replication stress.Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complexHow MCM loading and spreading specify eukaryotic DNA replication initiation sitesReplication stress: getting back on trackReplication fork instability and the consequences of fork collisions from rereplicationThe Causes and Consequences of Topological Stress during DNA ReplicationAn Mcm10 Mutant Defective in ssDNA Binding Shows Defects in DNA Replication InitiationXPF-ERCC1 acts in Unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP/SLX4A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA StrandsEukaryotic genome instability in light of asymmetric DNA replicationHelicase loading at chromosomal origins of replicationThe Dbf4-Cdc7 kinase promotes Mcm2-7 ring opening to allow for single-stranded DNA extrusion and helicase assembly.Structural and mechanistic insights into Mcm2-7 double-hexamer assembly and functionCMG-Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome.Eukaryotic Replicative Helicase Subunit Interaction with DNA and Its Role in DNA Replication.An intact Mcm10 coiled-coil interaction surface is important for origin melting, helicase assembly and the recruitment of Pol-α to Mcm2-7A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2-7 onto DNAMcm10 plays an essential role in origin DNA unwinding after loading of the CMG componentsChromatin replication and epigenome maintenance.
P2860
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P2860
Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Selective bypass of a lagging ...... otic replicative DNA helicase.
@en
type
label
Selective bypass of a lagging ...... otic replicative DNA helicase.
@en
prefLabel
Selective bypass of a lagging ...... otic replicative DNA helicase.
@en
P2093
P2860
P50
P1433
P1476
Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase
@en
P2093
Angelo Guainazzi
Jerard Hurwitz
Orlando D Schärer
The Vinh Ho
Vladimir P Bermudez
P2860
P304
P356
10.1016/J.CELL.2011.07.045
P407
P577
2011-09-01T00:00:00Z