BYL719, a new α-specific PI3K inhibitor: single administration and in combination with conventional chemotherapy for the treatment of osteosarcoma.
about
Osteosarcoma: Cells-of-Origin, Cancer Stem Cells, and Targeted TherapiesPI3K isoform-selective inhibitors: next-generation targeted cancer therapiesLong noncoding RNAs in the progression, metastasis, and prognosis of osteosarcomaEvaluation of In Vitro Activity of the Class I PI3K Inhibitor Buparlisib (BKM120) in Pediatric Bone and Soft Tissue SarcomasComplementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcomaPreclinical mouse models of osteosarcomaTargeting protein kinases to reverse multidrug resistance in sarcoma.PI3K p110β isoform synergizes with JNK in the regulation of glioblastoma cell proliferation and migration through Akt and FAK inhibition.Oncogenic and Therapeutic Targeting of PTEN Loss in Bone Malignancies.Targeting non-receptor tyrosine kinases using small molecule inhibitors: an overview of recent advances.The use of 18F-Fluoro-deoxy-glucose positron emission tomography (18F-FDG PET) as a non-invasive pharmacodynamic biomarker to determine the minimally pharmacologically active dose of AZD8835, a novel PI3Kα inhibitor.Specific inhibition of p110α subunit of PI3K: putative therapeutic strategy for KRAS mutant colorectal cancersSystematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma.Small animal models for the study of bone sarcoma pathogenesis:characteristics, therapeutic interests and limitations.Novel molecular insights and new therapeutic strategies in osteosarcoma
P2860
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P2860
BYL719, a new α-specific PI3K inhibitor: single administration and in combination with conventional chemotherapy for the treatment of osteosarcoma.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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2014年學術文章
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name
BYL719, a new α-specific PI3K ...... the treatment of osteosarcoma.
@en
type
label
BYL719, a new α-specific PI3K ...... the treatment of osteosarcoma.
@en
prefLabel
BYL719, a new α-specific PI3K ...... the treatment of osteosarcoma.
@en
P2093
P2860
P356
P1476
BYL719, a new α-specific PI3K ...... the treatment of osteosarcoma.
@en
P2093
Benjamin Ory
Bérengère Gobin
Céline Charrier
François Lamoureux
Françoise Redini
Frédéric Lezot
Marc Baud' Huin
Rachel Lanel
Séverine Battaglia
P2860
P304
P356
10.1002/IJC.29040
P577
2014-06-30T00:00:00Z