Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.
about
Mutations of PIK3CA in gastric adenocarcinomaIdentification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1Functional effects of PTPN11 (SHP2) mutations causing LEOPARD syndrome on epidermal growth factor-induced phosphoinositide 3-kinase/AKT/glycogen synthase kinase 3beta signalingShould individual PI3 kinase isoforms be targeted in cancer?Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gammaFBXL2- and PTPL1-mediated degradation of p110-free p85β regulatory subunit controls the PI(3)K signalling cascadePTEN function: how normal cells control it and tumour cells lose itPKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase.A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signalingAnalysis of the genome to personalize therapy for melanomamTOR inhibitors in advanced renal cell carcinomaProtean PTEN: form and functionDe novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromesThe PI3K pathway as drug target in human cancerRetroviral expression of a kinase-defective IGF-I receptor suppresses growth and causes apoptosis of CHO and U87 cells in-vivo.Topographical expression of class IA and class II phosphoinositide 3-kinase enzymes in normal human tissues is consistent with a role in differentiationPI3 kinase is important for Ras, MEK and Erk activation of Epo-stimulated human erythroid progenitorsThe origin and role of innate lymphoid cells in the lungThe Inositide Signaling Pathway As a Target for Treating Gastric Cancer and Colorectal CancerAdvances in targeted and immunobased therapies for colorectal cancer in the genomic eraPharmacodynamic Biomarker Development for PI3K Pathway TherapeuticsThe Potential of Vitamin D-Regulated Intracellular Signaling Pathways as Targets for Myeloid Leukemia TherapyTargeting of erbB3 receptor to overcome resistance in cancer treatmentDual pharmacological targeting of the MAP kinase and PI3K/mTOR pathway in preclinical models of colorectal cancerThe structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutationsA frequent kinase domain mutation that changes the interaction between PI3K and the membraneThe p110δ structure: mechanisms for selectivity and potency of new PI(3)K inhibitorsDiscovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of RapamycinCDK 4/6 inhibitors sensitize PIK3CA mutant breast cancer to PI3K inhibitors.Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.Everolimus in the management of metastatic renal cell carcinoma: an evidence-based review of its place in therapyCell-cell signaling by direct contact increases cell proliferation via a PI3K-dependent signalKnockdown of MTP18, a novel phosphatidylinositol 3-kinase-dependent protein, affects mitochondrial morphology and induces apoptosisOncogenic mutations of PIK3CA in human cancersMechanisms of MAdCAM-1 gene expression in human intestinal microvascular endothelial cellsNeuroprotective Effects of Salidroside in the MPTP Mouse Model of Parkinson's Disease: Involvement of the PI3K/Akt/GSK3β PathwayCurrent issues in malignant pleural mesothelioma evaluation and managementARID1A gene silencing reduces the sensitivity of ovarian clear cell carcinoma to cisplatinMulti-level targeting of the phosphatidylinositol-3-kinase pathway in non-small cell lung cancer cellsResveratrol inhibits LPS-induced MAPKs activation via activation of the phosphatidylinositol 3-kinase pathway in murine RAW 264.7 macrophage cells
P2860
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P2860
Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Cellular function of phosphoin ...... ment, homeostasis, and cancer.
@ast
Cellular function of phosphoin ...... ment, homeostasis, and cancer.
@en
Cellular function of phosphoin ...... ment, homeostasis, and cancer.
@nl
type
label
Cellular function of phosphoin ...... ment, homeostasis, and cancer.
@ast
Cellular function of phosphoin ...... ment, homeostasis, and cancer.
@en
Cellular function of phosphoin ...... ment, homeostasis, and cancer.
@nl
prefLabel
Cellular function of phosphoin ...... ment, homeostasis, and cancer.
@ast
Cellular function of phosphoin ...... ment, homeostasis, and cancer.
@en
Cellular function of phosphoin ...... ment, homeostasis, and cancer.
@nl
P2093
P1476
Cellular function of phosphoin ...... pment, homeostasis, and cancer
@en
P2093
P304
P356
10.1146/ANNUREV.CELLBIO.17.1.615
P577
2001-01-01T00:00:00Z