RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis.
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Necroptosis in tumorigenesis, activation of anti-tumor immunity, and cancer therapyAn outline of necrosome triggersDeath in the fast lane: what's next for necroptosis?The two faces of receptor interacting protein kinase-1Programmed necrosis in the cross talk of cell death and inflammationDistinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosisEssential versus accessory aspects of cell death: recommendations of the NCCD 2015.RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8⁺ T cells.The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis.Programmed cell death and its role in inflammationCaspases: a molecular switch node in the crosstalk between autophagy and apoptosisHematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis.RIP kinases: key decision makers in cell death and innate immunity.Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3Structure guided design of potent and selective ponatinib-based hybrid inhibitors for RIPK1.RIPK3 expression in cervical cancer cells is required for PolyIC-induced necroptosis, IL-1α release, and efficient paracrine dendritic cell activation3-BrPA eliminates human bladder cancer cells with highly oncogenic signatures via engagement of specific death programs and perturbation of multiple signaling and metabolic determinants.The serine threonine kinase RIP3: lost and found.Sequential Engagement of Distinct MLKL Phosphatidylinositol-Binding Sites Executes Necroptosis.Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis.Therapeutic hypothermia attenuates tissue damage and cytokine expression after traumatic brain injury by inhibiting necroptosis in the rat.Necroptosis: an alternative cell death program defending against cancer.Therapeutic applications of TRAIL receptor agonists in cancer and beyond.RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4.Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosisRIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome.Cloaked in ubiquitin, a killer hides in plain sight: the molecular regulation of RIPK1.The diverse role of RIP kinases in necroptosis and inflammation.A tale of two domains - a structural perspective of the pseudokinase, MLKL.Emerging Roles for RIPK1 and RIPK3 in Pathogen-Induced Cell Death and Host Immunity.CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3.Necrosome core machinery: MLKL.Necroptosis-independent signaling by the RIP kinases in inflammation.Post-translational control of RIPK3 and MLKL mediated necroptotic cell death.RIPK3 Restricts Viral Pathogenesis via Cell Death-Independent Neuroinflammation.Dying cells actively regulate adaptive immune responses.Controlled detonation: evolution of necroptosis in pathogen defense.Insane in the membrane: a structural perspective of MLKL function in necroptosis.The Inflammatory Signal Adaptor RIPK3: Functions Beyond Necroptosis.Complex Pathologic Roles of RIPK1 and RIPK3: Moving Beyond Necroptosis.
P2860
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P2860
RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis.
@en
type
label
RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis.
@en
prefLabel
RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis.
@en
P2093
P2860
P50
P356
P1476
RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis
@en
P2093
P2860
P2888
P304
P356
10.1038/CDD.2014.76
P577
2014-06-06T00:00:00Z