Pulsatile exposure to simulated reflux leads to changes in gene expression in a 3D model of oesophageal mucosa.
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Hnf4α is a key gene that can generate columnar metaplasia in oesophageal epithelium.Controlled bile acid exposure to oesophageal mucosa causes up-regulation of nuclear γ-H2AX possibly via iNOS induction.Production, Characterization and Potential Uses of a 3D Tissue-engineered Human Esophageal Mucosal ModelRocking media over ex vivo corneas improves this model and allows the study of the effect of proinflammatory cytokines on wound healing.
P2860
Pulsatile exposure to simulated reflux leads to changes in gene expression in a 3D model of oesophageal mucosa.
description
2014 nî lūn-bûn
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name
Pulsatile exposure to simulate ...... D model of oesophageal mucosa.
@en
Pulsatile exposure to simulate ...... D model of oesophageal mucosa.
@nl
type
label
Pulsatile exposure to simulate ...... D model of oesophageal mucosa.
@en
Pulsatile exposure to simulate ...... D model of oesophageal mucosa.
@nl
prefLabel
Pulsatile exposure to simulate ...... D model of oesophageal mucosa.
@en
Pulsatile exposure to simulate ...... D model of oesophageal mucosa.
@nl
P2093
P2860
P50
P356
P1476
Pulsatile exposure to simulate ...... 3D model of oesophageal mucosa
@en
P2093
Jonathan P Bury
Paul R Heath
Sheila MacNeil
Zoe Nicholls
P2860
P304
P356
10.1111/IEP.12083
P577
2014-04-08T00:00:00Z