TRAF6 stimulates the tumor-promoting effects of TGFβ type I receptor through polyubiquitination and activation of presenilin 1.
about
TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1Two Paralogous Tetraspanins TSP-12 and TSP-14 Function with the ADAM10 Metalloprotease SUP-17 to Promote BMP Signaling in Caenorhabditis elegansMammary epithelial cell phagocytosis downstream of TGF-β3 is characterized by adherens junction reorganization.APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain.Transforming growth factor-β promotes aggressiveness and invasion of clear cell renal cell carcinoma.Regulated intramembrane proteolysis of the TGFβ type I receptor conveys oncogenic signals.Epithelial Plasticity in Cancer: Unmasking a MicroRNA Network for TGF-β-, Notch-, and Wnt-Mediated EMT.Tumor necrosis factor receptor- associated factor 6 (TRAF6) regulation of development, function, and homeostasis of the immune system.Matters of context guide future research in TGFβ superfamily signaling.TGF-β Signaling from Receptors to Smads.Signaling Receptors for TGF-β Family Members.TRAF6 promotes TGFβ-induced invasion and cell-cycle regulation via Lys63-linked polyubiquitination of Lys178 in TGFβ type I receptor.Signaling Cross Talk between TGF-β/Smad and Other Signaling Pathways.Targeting TGF-β Signaling for Therapeutic Gain.C. elegans SMA-10 regulates BMP receptor trafficking.The kinase MST4 limits inflammatory responses through direct phosphorylation of the adaptor TRAF6.The SUMO guards for SNAIL.A Dithiol Compound Binds to the Zinc Finger Protein TRAF6 and Suppresses Its Ubiquitination.Pro-invasive properties of Snail1 are regulated by sumoylation in response to TGFβ stimulation in cancer.Regulated intramembrane proteolysis: emergent role in cell signalling pathways.VHL status regulates transforming growth factor-β signaling pathways in renal cell carcinoma.Genetic Alterations of TRAF Proteins in Human CancersTRAF6Targeting TGF-β Signaling in Kidney Fibrosis
P2860
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P2860
TRAF6 stimulates the tumor-promoting effects of TGFβ type I receptor through polyubiquitination and activation of presenilin 1.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
TRAF6 stimulates the tumor-pro ...... nd activation of presenilin 1.
@en
TRAF6 stimulates the tumor-pro ...... nd activation of presenilin 1.
@nl
type
label
TRAF6 stimulates the tumor-pro ...... nd activation of presenilin 1.
@en
TRAF6 stimulates the tumor-pro ...... nd activation of presenilin 1.
@nl
prefLabel
TRAF6 stimulates the tumor-pro ...... nd activation of presenilin 1.
@en
TRAF6 stimulates the tumor-pro ...... nd activation of presenilin 1.
@nl
P2093
P2860
P50
P1433
P1476
TRAF6 stimulates the tumor-pro ...... nd activation of presenilin 1.
@en
P2093
Anders Bergh
Anders Wallenius
Carl-Henrik Heldin
Guangxiang Zang
P2860
P356
10.1126/SCISIGNAL.2004207
P577
2014-01-07T00:00:00Z