about
TRAF6 promotes TGFβ-induced invasion and cell-cycle regulation via Lys63-linked polyubiquitination of Lys178 in TGFβ type I receptor.TRAF6 stimulates the tumor-promoting effects of TGFβ type I receptor through polyubiquitination and activation of presenilin 1.TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer.
P50
description
investigador
@es
researcher
@en
name
Reshma Sundar
@en
type
label
Reshma Sundar
@en
prefLabel
Reshma Sundar
@en
P31
P496
0000-0001-8737-8302