Internalized PCSK9 dissociates from recycling LDL receptors in PCSK9-resistant SV-589 fibroblasts
about
Hypercholesterolemia, low density lipoprotein receptor and proprotein convertase subtilisin/kexin-type 9Trafficking Dynamics of PCSK9-Induced LDLR Degradation: Focus on Human PCSK9 Mutations and C-Terminal DomainProprotein convertase subtilisin kexin type 9 promotes intestinal overproduction of triglyceride-rich apolipoprotein B lipoproteins through both low-density lipoprotein receptor-dependent and -independent mechanisms.On the function and homeostasis of PCSK9: reciprocal interaction with LDLR and additional lipid effects.PCSK9 inhibition fails to alter hepatic LDLR, circulating cholesterol, and atherosclerosis in the absence of ApoE.Investigational therapies for the treatment of atherosclerosis.Investigation of highly expressed PCSK9 in atherosclerotic plaques and ox-LDL-induced endothelial cell apoptosis.
P2860
Q26786549-A70879D1-BE58-454E-B9FB-FFAE1F06959CQ27339783-32CFBC80-1406-404D-B283-1DB1C5D11CC4Q33970677-4BA67BBF-BED4-4391-AAE4-24F4100B2637Q36035643-6757C664-4F55-4C5F-9E3F-1AB6237B29D7Q36196833-D4A075EE-565D-4823-BB9C-1A3A09EA7CF2Q38214386-2C12030F-BE81-478F-8B0A-A1357E059489Q42347016-4EB195C6-C0D7-415B-B86D-6B9E367EEEDF
P2860
Internalized PCSK9 dissociates from recycling LDL receptors in PCSK9-resistant SV-589 fibroblasts
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
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2013年论文
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2013年论文
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name
Internalized PCSK9 dissociates ...... 9-resistant SV-589 fibroblasts
@en
Internalized PCSK9 dissociates ...... -resistant SV-589 fibroblasts.
@nl
type
label
Internalized PCSK9 dissociates ...... 9-resistant SV-589 fibroblasts
@en
Internalized PCSK9 dissociates ...... -resistant SV-589 fibroblasts.
@nl
prefLabel
Internalized PCSK9 dissociates ...... 9-resistant SV-589 fibroblasts
@en
Internalized PCSK9 dissociates ...... -resistant SV-589 fibroblasts.
@nl
P2093
P2860
P356
P1476
Internalized PCSK9 dissociates ...... 9-resistant SV-589 fibroblasts
@en
P2093
My-Anh Nguyen
Tanja Kosenko
Thomas A Lagace
P2860
P304
P356
10.1194/JLR.M044156
P577
2013-12-02T00:00:00Z