Exploring the chemical space of G-quadruplex binders: discovery of a novel chemotype targeting the human telomeric sequence.
about
Docking Screens for Novel Ligands Conferring New Biology.Specific targeting of telomeric multimeric G-quadruplexes by a new triaryl-substituted imidazole.Mechanistic insight into ligand binding to G-quadruplex DNABis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplexDirectly lighting up RNA G-quadruplexes from test tubes to living human cells.Development of an Optimized Protocol for NMR Metabolomics Studies of Human Colon Cancer Cell Lines and First Insight from Testing of the Protocol Using DNA G-Quadruplex Ligands as Novel Anti-Cancer Drugs.Thioflavin T as an efficient fluorescence sensor for selective recognition of RNA G-quadruplexes.Helicases, G4-DNAs, and drug design.Noncanonical DNA secondary structures as drug targets: the prospect of the i-motif.Targeting unimolecular G-quadruplex nucleic acids: a new paradigm for the drug discovery?Looking for efficient G-quadruplex ligands: evidence for selective stabilizing properties and telomere damage by drug-like molecules.Ligand-induced conformational preorganization of loops of c-MYC G-quadruplex DNA and its implications in structure-specific drug design.G-quadruplex virtual drug screening: A review
P2860
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P2860
Exploring the chemical space of G-quadruplex binders: discovery of a novel chemotype targeting the human telomeric sequence.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Exploring the chemical space o ...... the human telomeric sequence.
@en
Exploring the chemical space o ...... the human telomeric sequence.
@nl
type
label
Exploring the chemical space o ...... the human telomeric sequence.
@en
Exploring the chemical space o ...... the human telomeric sequence.
@nl
prefLabel
Exploring the chemical space o ...... the human telomeric sequence.
@en
Exploring the chemical space o ...... the human telomeric sequence.
@nl
P2093
P50
P356
P1476
Exploring the chemical space o ...... the human telomeric sequence.
@en
P2093
Andrea Cavalli
Carmen D'Angelo
Chiara Cingolani
Claudia Sissi
Odra Pinato
P304
P356
10.1021/JM401185B
P407
P50
P577
2013-11-27T00:00:00Z