ATR-Chk1-APC/CCdh1-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress
about
The multifaceted roles of the HORMA domain in cellular signalingFunctional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesisEukaryotic DNA polymerase ζA high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage responseThe potent Cdc7-Dbf4 (DDK) kinase inhibitor XL413 has limited activity in many cancer cell lines and discovery of potential new DDK inhibitor scaffoldsDDK dependent regulation of TOP2A at centromeres revealed by a chemical genetics approachRegulation and roles of Cdc7 kinase under replication stress.The role of Dbf4-dependent protein kinase in DNA polymerase ζ-dependent mutagenesis in Saccharomyces cerevisiae.SCF(FBXW7α) modulates the intra-S-phase DNA-damage checkpoint by regulating Polo like kinase-1 stabilityIdentification of novel DNA-damage tolerance genes reveals regulation of translesion DNA synthesis by nucleophosmin.The fork and the kinase: a DNA replication tale from a CHK1 perspective.Subcellular proteomic approach for identifying the signaling effectors of protein kinase C-β₂ under high glucose conditions in human umbilical vein endothelial cellsFeedback regulation between atypical E2Fs and APC/CCdh1 coordinates cell cycle progression.Candida albicans Dbf4-dependent Cdc7 kinase plays a novel role in the inhibition of hyphal development.Common Chemical Inductors of Replication Stress: Focus on Cell-Based Studies.Controlling the response to DNA damage by the APC/C-Cdh1.New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stressATR-mediated phosphorylation of FANCI regulates dormant origin firing in response to replication stress.The Role of the Transcriptional Response to DNA Replication Stress.Sustained E2F-Dependent Transcription Is a Key Mechanism to Prevent Replication-Stress-Induced DNA Damage.p53 controls CDC7 levels to reinforce G1 cell cycle arrest upon genotoxic stress.Erratum to: Controlling the response to DNA damage by the APC/C-Cdh1.ATR kinase inhibition induces unscheduled origin firing through a Cdc7-dependent association between GINS and And-1.Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer.p53 gain-of-function mutations increase Cdc7-dependent replication initiation.DDK Has a Primary Role in Processing Stalled Replication Forks to Initiate Downstream Checkpoint SignalingControl of DNA Replication Initiation by Ubiquitin
P2860
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P2860
ATR-Chk1-APC/CCdh1-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
ATR-Chk1-APC/CCdh1-dependent s ...... ypass under replication stress
@en
ATR-Chk1-APC/CCdh1-dependent stabilization of Cdc7-ASK
@nl
type
label
ATR-Chk1-APC/CCdh1-dependent s ...... ypass under replication stress
@en
ATR-Chk1-APC/CCdh1-dependent stabilization of Cdc7-ASK
@nl
prefLabel
ATR-Chk1-APC/CCdh1-dependent s ...... ypass under replication stress
@en
ATR-Chk1-APC/CCdh1-dependent stabilization of Cdc7-ASK
@nl
P2093
P2860
P356
P1433
P1476
ATR-Chk1-APC/CCdh1-dependent s ...... ypass under replication stress
@en
P2093
Eva Vesela
Hisao Masai
Iva Protivankova
Kenji Watanabe
Martin Mistrik
Masayuki Yamada
MyungHee Lee
Niels Mailand
P2860
P304
P356
10.1101/GAD.224568.113
P577
2013-11-01T00:00:00Z