Antibody neutralization poses a barrier to intravitreal adeno-associated viral vector gene delivery to non-human primates - Wikidata - awgldk - TriplyDB

Antibody neutralization poses a barrier to intravitreal adeno-associated viral vector gene delivery to non-human primates

Antibody neutralization poses a barrier to intravitreal adeno-associated viral vector gene delivery to non-human primates

http://www.wikidata.org/entity/Q39076892

about

Engineering antibody-like inhibitors to prevent and treat HIV-1 infection.Non-viral therapeutic approaches to ocular diseases: An overview and future directions Strategies for targeting primate neural circuits with viral vectors.Gene therapy for age-related macular degeneration.CRISPR-Cas9: a new and promising player in gene therapy.Recent advances in gene therapy for lysosomal storage disorders.Application of polyploid adeno-associated virus vectors for transduction enhancement and neutralizing antibody evasion.A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina.Advances in optogenetic and chemogenetic methods to study brain circuits in non-human primates.Retinal Gene Therapy: Surgical Vector Delivery in the Translation to Clinical Trials.AAV9-mediated engineering of autotransplanted kidney of non-human primates.AAV-mediated delivery of optogenetic constructs to the macaque brain triggers humoral immune responses.Highly Efficient Delivery of Adeno-Associated Viral Vectors to the Primate Retina.Multiple Administrations of Viral Nanoparticles Alter in Vivo Behavior-Insights from Intravital Microscopy.Viral/Nonviral Chimeric Nanoparticles To Synergistically Suppress Leukemia Proliferation via Simultaneous Gene Transduction and Silencing.Long-term restoration of visual function in end-stage retinal degeneration using subretinal human melanopsin gene therapy.Neutralizing Antibodies Against Adeno-Associated Virus (AAV): Measurement and Influence on Retinal Gene Delivery.Current and Future Treatments for Lysosomal Storage Disorders.Screening for Neutralizing Antibodies Against Natural and Engineered AAV Capsids in Nonhuman Primate Retinas.AAV8-antiVEGFfab Ocular Gene Transfer for Neovascular Age-Related Macular Degeneration.Noninvasive gene delivery to foveal cones for vision restoration.Efficacy and Safety of Glycosidic Enzymes for Improved Gene Delivery to the Retina following Intravitreal Injection in Mice.Non-Primate Lentiviral Vectors and Their Applications in Gene Therapy for Ocular Disorders.Adeno-Associated Virus Neutralizing Antibodies in Large Animals and Their Impact on Brain Intraparenchymal Gene Transfer

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P2860

Antibody neutralization poses a barrier to intravitreal adeno-associated viral vector gene delivery to non-human primates

http://www.wikidata.org/entity/Q39076892

description

2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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name

Antibody neutralization poses ...... delivery to non-human primates

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Antibody neutralization poses ...... elivery to non-human primates.

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Antibody neutralization poses ...... delivery to non-human primates

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Antibody neutralization poses ...... delivery to non-human primates

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Antibody neutralization poses ...... delivery to non-human primates

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D V Schaffer

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J M Strazzeri

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L Yin

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M A Kotterman

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W H Merigan

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P2860

A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial

A viral assembly factor promotes AAV2 capsid formation in the nucleolus

Safety and efficacy of gene transfer for Leber's congenital amaurosis

Human RPE65 gene therapy for Leber congenital amaurosis: persistence of early visual improvements and safety at 1 year

Directed evolution of adeno-associated virus to an infectious respiratory virus

Immunology of AAV-Mediated Gene Transfer in the Eye

Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial

Effect of gene therapy on visual function in Leber's congenital amaurosis

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116-126

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10.1038/GT.2014.115

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2

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22

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John G. Flannery

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25503696

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