Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening.

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19 F NMR isotropic chemical shift for efficient screening of fluorinated fragments which are racemates and/or display multiple conformers.Chemical Space Expansion of Bromodomain Ligands Guided by in Silico Virtual Couplings (AutoCouple).

P2860

Q48315190-6F9B27BD-697D-4174-816E-A7ECF7F87DBB Q52659146-221334B6-99AC-426E-80B3-38B29DBFD69A

P2860

Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening.

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http://www.wikidata.org/entity/Q39085471

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2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening.

@en

Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening.

@nl

type

Item

label

Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening.

@en

Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening.

@nl

prefLabel

Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening.

@en

Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening.

@nl

P1476

Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening.

@en

P2093

Andrew L Hopkins

http://www.w3.org/2001/XMLSchema#string

Iva Navratilova

http://www.w3.org/2001/XMLSchema#string

Panagis Filappakopoulos

http://www.w3.org/2001/XMLSchema#string

Sarah Picaud

http://www.w3.org/2001/XMLSchema#string

Tonia Aristotelous

http://www.w3.org/2001/XMLSchema#string

P2860

Selective inhibition of BET bromodomains

Histone recognition and large-scale structural analysis of the human bromodomain family

Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain

Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation

The structural basis of protein acetylation by the p300/CBP transcriptional coactivator

Suppression of inflammation by a synthetic histone mimic

Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit

Targeting Low-Druggability Bromodomains: Fragment Based Screening and Inhibitor Design against the BAZ2B Bromodomain

Structure of the p300 catalytic core and implications for chromatin targeting and HAT regulation

Different orientations of low-molecular-weight fragments in the binding pocket of a BRD4 bromodomain

P304

1213-1218

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1021/ACSMEDCHEMLETT.6B00154

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Stefan Knapp

P577

2016-09-20T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

27994766

http://www.w3.org/2001/XMLSchema#string

P921

biosensing technique

P932

5150684

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Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening.

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P2860

P2860

Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P921

P932