A genetically engineered oncolytic adenovirus decoys and lethally traps quiescent cancer stem-like cells in S/G2/M phases.
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Telomere and Telomerase Therapeutics in CancerCancer cells mimic in vivo spatial-temporal cell-cycle phase distribution and chemosensitivity in 3-dimensional Gelfoam® histoculture but not 2-dimensional culture as visualized with real-time FUCCI imaging.Improved Resection and Outcome of Colon-Cancer Liver Metastasis with Fluorescence-Guided Surgery Using In Situ GFP Labeling with a Telomerase-Dependent Adenovirus in an Orthotopic Mouse ModelOncolytic viruses against cancer stem cells: A promising approach for gastrointestinal cancerPotent anti-tumour activity of a novel conditionally replicating adenovirus for melanoma via inhibition of migration and invasion.Wilms' tumor blastemal stem cells dedifferentiate to propagate the tumor bulk.Selective methioninase-induced trap of cancer cells in S/G2 phase visualized by FUCCI imaging confers chemosensitivity.Application of GFP imaging in cancer.Efficacy of a Cell-Cycle Decoying Killer Adenovirus on 3-D Gelfoam®-Histoculture and Tumor-Sphere Models of Chemo-Resistant Stomach Carcinomatosis Visualized by FUCCI Imaging.Tumor-targeting Salmonella typhimurium A1-R decoys quiescent cancer cells to cycle as visualized by FUCCI imaging and become sensitive to chemotherapyTumor-targeting adenovirus OBP-401 inhibits primary and metastatic tumor growth of triple-negative breast cancer in orthotopic nude-mouse modelsUnusual prolongation of radiation-induced G2 arrest in tumor xenografts derived from HeLa cellsSphere-derived tumor cells exhibit impaired metastasis by a host-mediated quiescent phenotype.Experimental Curative Fluorescence-guided Surgery of Highly Invasive Glioblastoma Multiforme Selectively Labeled With a Killer-reporter Adenovirus.Ablation of MCL1 expression by virally induced microRNA-29 reverses chemoresistance in human osteosarcomas.Adenoviral targeting of malignant melanoma for fluorescence-guided surgery prevents recurrence in orthotopic nude-mouse models.Tumor-specific cell-cycle decoy by Salmonella typhimurium A1-R combined with tumor-selective cell-cycle trap by methioninase overcome tumor intrinsic chemoresistance as visualized by FUCCI imaging.Dynamic fluorescent imaging with the activatable probe, γ-glutamyl hydroxymethyl rhodamine green in the detection of peritoneal cancer metastases: Overcoming the problem of dilution when using a sprayable optical probe.Fluorescence-guided surgery of a highly-metastatic variant of human triple-negative breast cancer targeted with a cancer-specific GFP adenovirus prevents recurrence.Development of recombinant methioninase to target the general cancer-specific metabolic defect of methionine dependence: a 40-year odyssey.OBP-401-GFP telomerase-dependent adenovirus illuminates and kills high-metastatic more effectively than low-metastatic triple-negative breast cancer in vitro.Cell-cycle-dependent drug-resistant quiescent cancer cells induce tumor angiogenesis after chemotherapy as visualized by real-time FUCCI imaging.Timed, sequential administration of paclitaxel improves its cytotoxic effectiveness in a cell culture model.Nanoparticle albumin-bound-paclitaxel: a limited improvement under the current therapeutic paradigm of pancreatic cancerOvercoming Therapeutic Resistance of Bone Sarcomas: Overview of the Molecular Mechanisms and Therapeutic Targets for Bone Sarcoma Stem Cells.VSV based virotherapy in ovarian cancer: the past, the present and …future?Role of zoledronic acid in oncolytic virotherapy: Promotion of antitumor effect and prevention of bone destruction.Targeting strategies of adenovirus‑mediated gene therapy and virotherapy for prostate cancer (Review).Therapeutic Cell-Cycle-Decoy Efficacy of a Telomerase-Dependent Adenovirus in an Orthotopic Model of Chemotherapy-Resistant Human Stomach Carcinomatosis Peritonitis Visualized With FUCCI Imaging.Oncolytic Virotherapy versus Cancer Stem Cells: A Review of Approaches and Mechanisms.Oncolytic Adenoviruses in Gastrointestinal Cancers.Oncolytic virotherapy in upper gastrointestinal tract cancers.
P2860
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P2860
A genetically engineered oncolytic adenovirus decoys and lethally traps quiescent cancer stem-like cells in S/G2/M phases.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
A genetically engineered oncol ...... m-like cells in S/G2/M phases.
@en
A genetically engineered oncol ...... m-like cells in S/G2/M phases.
@nl
type
label
A genetically engineered oncol ...... m-like cells in S/G2/M phases.
@en
A genetically engineered oncol ...... m-like cells in S/G2/M phases.
@nl
prefLabel
A genetically engineered oncol ...... m-like cells in S/G2/M phases.
@en
A genetically engineered oncol ...... m-like cells in S/G2/M phases.
@nl
P2093
P50
P1476
A genetically engineered oncol ...... em-like cells in S/G2/M phases
@en
P2093
Futoshi Uno
Hiroyuki Kishimoto
Masahiko Nishizaki
Robert M Hoffman
Shinji Kuroda
Shuya Yano
Toshiyoshi Fujiwara
Yasuhiro Shirakawa
Yasuo Urata
Yuuri Hashimoto
P304
P356
10.1158/1078-0432.CCR-13-0742
P407
P577
2013-09-30T00:00:00Z