Carboxamide SIRT1 inhibitors block DBC1 binding via an acetylation-independent mechanism.
about
Synthesis and Assay of SIRT1-Activating CompoundsSirt1 carboxyl-domain is an ATP-repressible domain that is transferrable to other proteins.Mathematical Model of the Firefly Luciferase Complementation Assay Reveals a Non-Linear Relationship between the Detected Luminescence and the Affinity of the Protein Pair Being AnalyzedActive regulator of SIRT1 is required for cancer cell survival but not for SIRT1 activityhMOF acetylation of DBC1/CCAR2 prevents binding and inhibition of SirT1.CCAR2/DBC1 is required for Chk2-dependent KAP1 phosphorylation and repair of DNA damage.DBC1/CCAR2 and CCAR1 Are Largely Disordered Proteins that Have Evolved from One Common Ancestor.
P2860
Q28818352-000CEF4E-E687-4935-8861-D479C0C592AFQ33715990-CE598732-6556-42BB-B6AB-FAC57E1A0834Q35926186-9D362290-FEA0-41F2-9AB6-51E29B061AD1Q37350626-1C985BF1-2008-4204-8DA2-975E639141B9Q37469490-6A0713D0-C43D-4530-A752-6DE2D743B582Q38855040-F3020534-3130-4C10-BE34-703D55FA1561Q41545013-D8AF0AD6-6D0E-4D11-BD79-F55D583FA6AF
P2860
Carboxamide SIRT1 inhibitors block DBC1 binding via an acetylation-independent mechanism.
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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2013年论文
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2013年论文
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name
Carboxamide SIRT1 inhibitors block DBC1 binding via an acetylation-independent mechanism.
@en
Carboxamide SIRT1 inhibitors block DBC1 binding via an acetylation-independent mechanism.
@nl
type
label
Carboxamide SIRT1 inhibitors block DBC1 binding via an acetylation-independent mechanism.
@en
Carboxamide SIRT1 inhibitors block DBC1 binding via an acetylation-independent mechanism.
@nl
prefLabel
Carboxamide SIRT1 inhibitors block DBC1 binding via an acetylation-independent mechanism.
@en
Carboxamide SIRT1 inhibitors block DBC1 binding via an acetylation-independent mechanism.
@nl
P2093
P2860
P356
P1433
P1476
Carboxamide SIRT1 inhibitors block DBC1 binding via an acetylation-independent mechanism.
@en
P2093
Ana P Gomes
Christine Loh
George P Vlasuk
James L Ellis
Jeremy S Disch
Sean M Armour
Taylor Lg Doyle
P2860
P304
P356
10.4161/CC.25268
P577
2013-07-01T00:00:00Z