Protein kinase D links Gq-coupled receptors to cAMP response element-binding protein (CREB)-Ser133 phosphorylation in the heart. - Wikidata - awgldk - TriplyDB

Protein kinase D links Gq-coupled receptors to cAMP response element-binding protein (CREB)-Ser133 phosphorylation in the heart.

Protein kinase D links Gq-coupled receptors to cAMP response element-binding protein (CREB)-Ser133 phosphorylation in the heart.

http://www.wikidata.org/entity/Q39142718

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Genome-Wide Gene Expression Analysis Shows AKAP13-Mediated PKD1 Signaling Regulates the Transcriptional Response to Cardiac Hypertrophy Protein kinase C mechanisms that contribute to cardiac remodelling AEBP1 upregulation confers acquired resistance to BRAF (V600E) inhibition in melanoma A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo.Splice variants of enigma homolog, differentially expressed during heart development, promote or prevent hypertrophy.Protein kinase C-{delta} regulates the subcellular localization of Shc in H2O2-treated cardiomyocytes.Novel function of cardiac protein kinase D1 as a dynamic regulator of Ca2+ sensitivity of contraction Dipyridamole with low-dose aspirin augments the infarct size-limiting effects of simvastatin Protein kinase D isoforms are activated in an agonist-specific manner in cardiomyocytes.Lysophosphatidylcholine activates a novel PKD2-mediated signaling pathway that controls monocyte migration Cellular and molecular action of the mitogenic protein-deamidating toxin from Pasteurella multocida.Therapeutic efficacy of cardiosphere-derived cells in a transgenic mouse model of non-ischaemic dilated cardiomyopathy.Protein kinase D signaling: multiple biological functions in health and disease.Cyclic mechanical strain causes cAMP-response element binding protein activation by different pathways in cardiac fibroblasts.The C2 Domain and Altered ATP-Binding Loop Phosphorylation at Ser³⁵⁹ Mediate the Redox-Dependent Increase in Protein Kinase C-δ Activity Pasteurella multocida toxin interaction with host cells: entry and cellular effects.Protein kinase D3 is a pivotal activator of pathological cardiac hypertrophy by selectively increasing the expression of hypertrophic transcription factors.Regulation of protein kinase D1 activity.Defining the cellular repertoire of GPCRs identifies a profibrotic role for the most highly expressed receptor, protease-activated receptor 1, in cardiac fibroblasts.Mammalian target of rapamycin complex 1 (mTORC1) plays a role in Pasteurella multocida toxin (PMT)-induced protein synthesis and proliferation in Swiss 3T3 cells Cardiac actions of protein kinase C isoforms Protein kinase D2 contributes to TNF-α-induced epithelial mesenchymal transition and invasion via the PI3K/GSK-3β/β-catenin pathway in hepatocellular carcinoma Reactive oxygen species decrease cAMP response element binding protein expression in cardiomyocytes via a protein kinase D1-dependent mechanism that does not require Ser133 phosphorylation.GRK3 is a direct target of CREB activation and regulates neuroendocrine differentiation of prostate cancer cells.Emergency Spatiotemporal Shift: The Response of Protein Kinase D to Stress Signals in the Cardiovascular System.Rho/ROCK-dependent inhibition of 3T3-L1 adipogenesis by G-protein-deamidating dermonecrotic toxins: differential regulation of Notch1, Pref1/Dlk1, and β-catenin signaling.Enterovirus 71 modulates a COX-2/PGE2/cAMP-dependent viral replication in human neuroblastoma cells: role of the c-Src/EGFR/p42/p44 MAPK/CREB signaling pathway.β-adrenergic signaling inhibits Gq-dependent protein kinase D activation by preventing protein kinase D translocation.β1-adrenergic receptor O-glycosylation regulates N-terminal cleavage and signaling responses in cardiomyocytes.Phos-tag SDS-PAGE resolves agonist- and isoform-specific activation patterns for PKD2 and PKD3 in cardiomyocytes and cardiac fibroblasts.Regulation of PKD1-mediated Golgi to cell surface trafficking by Gαq subunits.The myocardial infarct size-limiting effect of sitagliptin is PKA-dependent, whereas the protective effect of pioglitazone is partially dependent on PKA.Protein kinase D1 autophosphorylation via distinct mechanisms at Ser744/Ser748 and Ser916.Targeting myocyte-specific enhancer factor 2D contributes to the suppression of cardiac hypertrophic growth by miR-92b-3p in mice.North American ginseng (Panax quinquefolius) suppresses β-adrenergic-dependent signalling, hypertrophy, and cardiac dysfunction.VEGF stimulates PKD-mediated CREB-dependent orphan nuclear receptor Nurr1 expression: role in VEGF-induced angiogenesis.

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P2860

Protein kinase D links Gq-coupled receptors to cAMP response element-binding protein (CREB)-Ser133 phosphorylation in the heart.

http://www.wikidata.org/entity/Q39142718

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Protein kinase D links Gq-coup ...... phosphorylation in the heart.

@en

Protein kinase D links Gq-coupled receptors to cAMP response element-binding protein

@nl

type

label

Protein kinase D links Gq-coup ...... phosphorylation in the heart.

@en

Protein kinase D links Gq-coupled receptors to cAMP response element-binding protein

@nl

prefLabel

Protein kinase D links Gq-coup ...... phosphorylation in the heart.

@en

Protein kinase D links Gq-coupled receptors to cAMP response element-binding protein

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

Protein kinase D links Gq-coup ...... phosphorylation in the heart.

@en

P2093

Brenda A Wilson

http://www.w3.org/2001/XMLSchema#string

Gerald W Dorn

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Hasnae Elouardighi

http://www.w3.org/2001/XMLSchema#string

Jianfen Guo

http://www.w3.org/2001/XMLSchema#string

Maria Obreztchikova

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Nazira Ozgen

http://www.w3.org/2001/XMLSchema#string

Susan F Steinberg

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P2860

Molecular cloning and characterization of the human protein kinase D2. A novel member of the protein kinase D family of serine threonine kinases

Mutations in the kinase Rsk-2 associated with Coffin-Lowry syndrome

MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts

Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5

The pleckstrin homology domain of protein kinase D interacts preferentially with the eta isoform of protein kinase C

Protein kinase D is a novel mediator of cardiac troponin I phosphorylation and regulates myofilament function

Distinct signaling functions for Shc isoforms in the heart

The C2 domain of PKCdelta is a phosphotyrosine binding domain.

Induction of NR4A orphan nuclear receptor expression in macrophages in response to inflammatory stimuli.

Dual actions of the Galpha(q) agonist Pasteurella multocida toxin to promote cardiomyocyte hypertrophy and enhance apoptosis susceptibility

P304

17009-17019

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P31

scholarly article

P356

10.1074/JBC.M709851200

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P407

P433

25

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P478

283

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P577

2008-03-31T00:00:00Z

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P698

18378685

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P921

phosphorylation

P932

2427335

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