The pleckstrin homology domain of protein kinase D interacts preferentially with the eta isoform of protein kinase C
about
Molecular cloning and characterization of the human protein kinase D2. A novel member of the protein kinase D family of serine threonine kinasesTyrosine phosphorylation of protein kinase D in the pleckstrin homology domain leads to activationSignal-dependent membrane targeting by pleckstrin homology (PH) domainsThe RAS effector RIN1 directly competes with RAF and is regulated by 14-3-3 proteins.Differential binding to and regulation of JAK2 by the SH2 domain and N-terminal region of SH2-bbetaPKD signaling and pancreatitisRegulation of protein kinase D by multisite phosphorylation. Identification of phosphorylation sites by mass spectrometry and characterization by site-directed mutagenesisRecruitment of protein kinase D to the trans-Golgi network via the first cysteine-rich domain.Protein kinase D is implicated in the reversible commitment to differentiation in primary cultures of mouse keratinocytesProtein kinase D interacts with neuronal nitric oxide synthase and phosphorylates the activatory residue serine 1412P2X7 receptors activate protein kinase D and p42/p44 mitogen-activated protein kinase (MAPK) downstream of protein kinase CProtein Kinase Inhibitors CK59 and CID755673 Alter Primary Human NK Cell Effector FunctionsThe actin filament-associated protein AFAP-110 is an adaptor protein that modulates changes in actin filament integrity.Phosphorylation of dynamin I on Ser-795 by protein kinase C blocks its association with phospholipids.Identification and cloning of Kidins220, a novel neuronal substrate of protein kinase D.Induced overexpression of protein kinase D1 stimulates mitogenic signaling in human pancreatic carcinoma PANC-1 cellsRole of protein kinase D signaling in pancreatic cancerProtein kinase Cδ mediates the activation of protein kinase D2 in plateletsRegulation of protein kinase D1 activity.PKD2 and RSK1 Regulate Integrin β4 Phosphorylation at Threonine 1736.CCK causes PKD1 activation in pancreatic acini by signaling through PKC-delta and PKC-independent pathwaysProtein kinase D signaling.Rapid protein kinase D1 signaling promotes migration of intestinal epithelial cells.PKCeta is required for beta1gamma2/beta3gamma2- and PKD-mediated transport to the cell surface and the organization of the Golgi apparatusSequential protein kinase C (PKC)-dependent and PKC-independent protein kinase D catalytic activation via Gq-coupled receptors: differential regulation of activation loop Ser(744) and Ser(748) phosphorylationProtein kinase Cdelta selectively regulates protein kinase D-dependent activation of NF-kappaB in oxidative stress signaling.Protein kinase D1 mediates NF-kappaB activation induced by cholecystokinin and cholinergic signaling in pancreatic acinar cellsProtein kinase D isoforms are expressed in rat and mouse primary sensory neurons and are activated by agonists of protease-activated receptor 2.Protein kinase D mediates synergistic expression of COX-2 induced by TNF-{alpha} and bradykinin in human colonic myofibroblasts.Protein kinase D1, a new molecular player in VEGF signaling and angiogenesis.Emergency Spatiotemporal Shift: The Response of Protein Kinase D to Stress Signals in the Cardiovascular System.Protein kinase D: a new player among the signaling proteins that regulate functions in the nervous system.The nuclear import of protein kinase D3 requires its catalytic activity.Protein kinase D links Gq-coupled receptors to cAMP response element-binding protein (CREB)-Ser133 phosphorylation in the heart.Novel PKCs activate ERK through PKD1 in MCF-7 cells.Conserved domains subserve novel mechanisms and functions in DKF-1, a Caenorhabditis elegans protein kinase D.Inositol phospholipids regulate the guanine-nucleotide-exchange factor Tiam1 by facilitating its binding to the plasma membrane and regulating GDP/GTP exchange on Rac1HSos1 contains a new amino-terminal regulatory motif with specific binding affinity for its pleckstrin homology domain.Protein kinase D complexes with C-Jun N-terminal kinase via activation loop phosphorylation and phosphorylates the C-Jun N-terminus.Structural requirements for localization and activation of protein kinase C mu (PKC mu) at the Golgi compartment.
P2860
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P2860
The pleckstrin homology domain of protein kinase D interacts preferentially with the eta isoform of protein kinase C
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The pleckstrin homology domain ...... ta isoform of protein kinase C
@ast
The pleckstrin homology domain ...... ta isoform of protein kinase C
@en
The pleckstrin homology domain ...... ta isoform of protein kinase C
@nl
type
label
The pleckstrin homology domain ...... ta isoform of protein kinase C
@ast
The pleckstrin homology domain ...... ta isoform of protein kinase C
@en
The pleckstrin homology domain ...... ta isoform of protein kinase C
@nl
prefLabel
The pleckstrin homology domain ...... ta isoform of protein kinase C
@ast
The pleckstrin homology domain ...... ta isoform of protein kinase C
@en
The pleckstrin homology domain ...... ta isoform of protein kinase C
@nl
P2093
P2860
P356
P1476
The pleckstrin homology domain ...... ta isoform of protein kinase C
@en
P2093
E Rozengurt
R T Waldron
T Iglesias
P2860
P304
P356
10.1074/JBC.274.14.9224
P407
P577
1999-04-02T00:00:00Z