The antipsychotic agent chlorpromazine induces autophagic cell death by inhibiting the Akt/mTOR pathway in human U-87MG glioma cells. - Wikidata - awgldk - TriplyDB

The antipsychotic agent chlorpromazine induces autophagic cell death by inhibiting the Akt/mTOR pathway in human U-87MG glioma cells.

The antipsychotic agent chlorpromazine induces autophagic cell death by inhibiting the Akt/mTOR pathway in human U-87MG glioma cells.

http://www.wikidata.org/entity/Q39149568

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Mitochondrial dysfunction in psychiatric morbidity: current evidence and therapeutic prospects Targeting autophagy to sensitive glioma to temozolomide treatment Endocytic Pathways Used by Andes Virus to Enter Primary Human Lung Endothelial Cells Characterization of HJ-PI01 as a novel Pim-2 inhibitor that induces apoptosis and autophagic cell death in triple-negative human breast cancer Endothelial-Monocyte Activating Polypeptide II Suppresses the In Vitro Glioblastoma-Induced Angiogenesis by Inducing Autophagy.Repositioning chlorpromazine for treating chemoresistant glioma through the inhibition of cytochrome c oxidase bearing the COX4-1 regulatory subunit.Monoclonal antibody against cell surface GRP78 as a novel agent in suppressing PI3K/AKT signaling, tumor growth, and metastasis.The contribution of lysosomotropism to autophagy perturbation.Huaier Extract Induces Autophagic Cell Death by Inhibiting the mTOR/S6K Pathway in Breast Cancer Cells.Puquitinib mesylate (XC-302) induces autophagy via inhibiting the PI3K/AKT/mTOR signaling pathway in nasopharyngeal cancer cells Autophagy inhibition uncovers the neurotoxic action of the antipsychotic drug olanzapine.A cell-based quantitative high-throughput image screening identified novel autophagy modulators Antidepressant indatraline induces autophagy and inhibits restenosis via suppression of mTOR/S6 kinase signaling pathway.Lysosomal adaptation: How cells respond to lysosomotropic compounds.Integrating multiple omics data for the discovery of potential Beclin-1 interactions in breast cancer.Repositioning antipsychotic chlorpromazine for treating colorectal cancer by inhibiting sirtuin 1 Repurposing antipsychotics as glioblastoma therapeutics: Potentials and challenges Penfluridol: An Antipsychotic Agent Suppresses Metastatic Tumor Growth in Triple-Negative Breast Cancer by Inhibiting Integrin Signaling Axis.Penfluridol suppresses pancreatic tumor growth by autophagy-mediated apoptosis.Applicability of gene expression and systems biology to develop pharmacogenetic predictors; antipsychotic-induced extrapyramidal symptoms as an example.Targeted pulmonary delivery of inducers of host macrophage autophagy as a potential host-directed chemotherapy of tuberculosis Mst1 regulates glioma cell proliferation via the AKT/mTOR signaling pathway.Network analysis of gene expression in mice provides new evidence of involvement of the mTOR pathway in antipsychotic-induced extrapyramidal symptoms.Combined EGFR and autophagy modulation impairs cell migration and enhances radiosensitivity in human glioblastoma cells.Ursolic acid improves podocyte injury caused by high glucose.Autophagy Induction by Endothelial-Monocyte Activating Polypeptide II Contributes to the Inhibition of Malignant Biological Behaviors by the Combination of EMAP II with Rapamycin in Human Glioblastoma.Enhanced human enterovirus 71 infection by endocytosis inhibitors reveals multiple entry pathways by enterovirus causing hand-foot-and-mouth diseases.Drug repurposing for the treatment of glioblastoma multiforme.Network analysis of gene expression in peripheral blood identifies mTOR and NF-κB pathways involved in antipsychotic-induced extrapyramidal symptoms.Developments in Blood-Brain Barrier Penetrance and Drug Repurposing for Improved Treatment of Glioblastoma The antipsychotic agent trifluoperazine hydrochloride suppresses triple-negative breast cancer tumor growth and brain metastasis by inducing G0/G1 arrest and apoptosis Glioma in Schizophrenia: Is the Risk Higher or Lower?Targeting Oncogene-Induced Autophagy: A New Approach in Cancer Therapy?

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The antipsychotic agent chlorpromazine induces autophagic cell death by inhibiting the Akt/mTOR pathway in human U-87MG glioma cells.

http://www.wikidata.org/entity/Q39149568

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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name

The antipsychotic agent chlorp ...... in human U-87MG glioma cells.

@en

The antipsychotic agent chlorp ...... in human U-87MG glioma cells.

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type

label

The antipsychotic agent chlorp ...... in human U-87MG glioma cells.

@en

The antipsychotic agent chlorp ...... in human U-87MG glioma cells.

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prefLabel

The antipsychotic agent chlorp ...... in human U-87MG glioma cells.

@en

The antipsychotic agent chlorp ...... in human U-87MG glioma cells.

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The antipsychotic agent chlorp ...... in human U-87MG glioma cells.

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P2093

Hong Ghi Lee

http://www.w3.org/2001/XMLSchema#string

Hyunjung Jade Lim

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Kyoung Sun Lee

http://www.w3.org/2001/XMLSchema#string

Soon Young Shin

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Yang-Kyu Choi

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Yoongho Lim

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Young Han Lee

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P2860

Inhibition of macroautophagy triggers apoptosis

Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

Formation process of autophagosome is traced with Apg8/Aut7p in yeast

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

Induction of autophagy and inhibition of tumorigenesis by beclin 1

Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21

The mTOR pathway and its role in human genetic diseases

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

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2080-2089

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10.1093/CARCIN/BGT169

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9

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34

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