Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.

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A Dual Topoisomerase Inhibitor of Intense Pro-Apoptotic and Antileukemic Nature for Cancer Treatment.Discovery of DNA Topoisomerase I Inhibitors with Low-Cytotoxicity Based on Virtual Screening from Natural Products.

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Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.

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2013 nî lūn-bûn

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Synthesis and biological evalu ...... tor of topoisomerase I and II.

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Synthesis and biological evalu ...... tor of topoisomerase I and II.

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Synthesis and biological evalu ...... tor of topoisomerase I and II.

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Synthesis and biological evalu ...... tor of topoisomerase I and II.

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Synthesis and biological evalu ...... tor of topoisomerase I and II.

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Synthesis and biological evalu ...... tor of topoisomerase I and II.

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P1476

Synthesis and biological evalu ...... tor of topoisomerase I and II.

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Chun-Yan Li

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Ding Li

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Jia-Heng Tan

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Lian-Quan Gu

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Lin-Kun An

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Ming-Hao Hu

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Pei-Fen Yao

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Shi-Liang Huang

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Shi-Tian Zhuo

http://www.w3.org/2001/XMLSchema#string

Shuo-Bin Chen

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P2860

DNA T OPOISOMERASES : Structure, Function, and Mechanism

Salvicine functions as novel topoisomerase II poison by binding to ATP pocket

Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics

Targeting DNA topoisomerase II in cancer chemotherapy

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Nonlinear partial differential equations and applications: The mechanism of topoisomerase I poisoning by a camptothecin analog

Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187

DNA topoisomerases

Apoptosis: biochemical aspects and clinical implications.

Mechanism of inhibition of the ATPase domain of human topoisomerase IIα by 1,4-benzoquinone, 1,2-naphthoquinone, 1,4-naphthoquinone, and 9,10-phenanthroquinone.

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3989-4005

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10.1039/C3OB40325D

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Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.

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P2860

P2860

Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.

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P698