In vivo assessment and dosimetry of 2 novel PDE10A PET radiotracers in humans: 18F-MNI-659 and 18F-MNI-654.
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Novel Radioligands for Cyclic Nucleotide Phosphodiesterase Imaging with Positron Emission Tomography: An Update on Developments Since 2012The role of dopamine and dopaminergic pathways in dystonia: insights from neuroimagingComparison of [(11)C]TZ1964B and [(18)F]MNI659 for PET imaging brain PDE10A in nonhuman primatesFunctional neuroimaging and chorea: a systematic review.Schizophrenia drug discovery and development in an evolving era: are new drug targets fulfilling expectations?Further evaluation of [11C]MP-10 as a radiotracer for phosphodiesterase 10A: PET imaging study in rhesus monkeys and brain tissue metabolite analysis.Preclinical evaluation of a promising C-11 labeled PET tracer for imaging phosphodiesterase 10A in the brain of living subjectA novel thermoregulatory role for PDE10A in mouse and human adipocytesCharacterization of [11C]Lu AE92686 as a PET radioligand for phosphodiesterase 10A in the nonhuman primate brainPhosphodiesterase 10A inhibitors: analysis of US/EP patents granted since 2012.Revisiting the Logan plot to account for non-negligible blood volume in brain tissue.Considerations in the Development of Reversibly Binding PET Radioligands for Brain Imaging.Tactics for preclinical validation of receptor-binding radiotracers.Phosphodiesterase 10 inhibitors in clinical development for CNS disorders.Radiosynthesis and biological evaluation of the new PDE10A radioligand [18 F]AQ28A.Loss of phosphodiesterase 10A expression is associated with progression and severity in Parkinson's disease.Evaluation of a novel PDE10A PET radioligand, [(11) C]T-773, in nonhuman primates: brain and whole body PET and brain autoradiography.Altered PDE10A expression detectable early before symptomatic onset in Huntington's disease.Molecular Imaging of PDE10A Knockout Mice with a Novel PET Radiotracer: [(11)C]T-773.In vivo characterization of two 18F-labeled PDE10A PET radioligands in nonhuman primate brains.Preclinical Characterization of the Phosphodiesterase 10A PET Tracer [(11)C]MK-8193.
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P2860
In vivo assessment and dosimetry of 2 novel PDE10A PET radiotracers in humans: 18F-MNI-659 and 18F-MNI-654.
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2014 nî lūn-bûn
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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2014年论文
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2014年论文
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name
In vivo assessment and dosimet ...... : 18F-MNI-659 and 18F-MNI-654.
@en
In vivo assessment and dosimet ...... : 18F-MNI-659 and 18F-MNI-654.
@nl
type
label
In vivo assessment and dosimet ...... : 18F-MNI-659 and 18F-MNI-654.
@en
In vivo assessment and dosimet ...... : 18F-MNI-659 and 18F-MNI-654.
@nl
prefLabel
In vivo assessment and dosimet ...... : 18F-MNI-659 and 18F-MNI-654.
@en
In vivo assessment and dosimet ...... : 18F-MNI-659 and 18F-MNI-654.
@nl
P2093
P1476
In vivo assessment and dosimet ...... s: 18F-MNI-659 and 18F-MNI-654
@en
P2093
Adriana Tavares
Caroline Papin
Danna Jennings
David Alagille
David Russell
Gilles Tamagnan
John Seibyl
Olivier Barret
Rikki Waterhouse
P304
P356
10.2967/JNUMED.113.122895
P407
P50
P577
2014-06-04T00:00:00Z