Development and validation of a liquid chromatographic-tandem mass spectrometric method for determination of piperaquine in plasma stable isotope labeled internal standard does not always compensate for matrix effects.
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Clinical trials of artesunate plus sulfadoxine-pyrimethamine for Plasmodium falciparum malaria in Afghanistan: maintained efficacy a decade after introductionDeclining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coastMetabolite identification of the antimalarial piperaquine in vivo using liquid chromatography-high-resolution mass spectrometry in combination with multiple data-mining tools in tandem.An overview of matrix effects in liquid chromatography-mass spectrometry.Population pharmacokinetic assessment of the effect of food on piperaquine bioavailability in patients with uncomplicated malaria.Critical topics in ensuring data quality in bioanalytical LC-MS method development.Population Pharmacokinetics and Antimalarial Pharmacodynamics of Piperaquine in Patients With Plasmodium vivax Malaria in ThailandApplication of screening experimental designs to assess chromatographic isotope effect upon isotope-coded derivatization for quantitative liquid chromatography-mass spectrometry.Open-label crossover study of primaquine and dihydroartemisinin-piperaquine pharmacokinetics in healthy adult thai subjects.A small amount of fat does not affect piperaquine exposure in patients with malaria.Randomized, double-blind, placebo-controlled trial of monthly versus bimonthly dihydroartemisinin-piperaquine chemoprevention in adults at high risk of malaria.Pharmacokinetics of piperaquine in pregnant women in Sudan with uncomplicated Plasmodium falciparum malariaSimultaneous determination of piperaquine and its N-oxidated metabolite in rat plasma using LC-MS/MS.A population pharmacokinetic model of piperaquine in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum malaria in Sudan.Dihydroartemisinin-piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study.Population pharmacokinetics and pharmacodynamics of piperaquine in children with uncomplicated falciparum malaria.Population Pharmacokinetics of Piperaquine in Young Ugandan Children Treated With Dihydroartemisinin-Piperaquine for Uncomplicated Malaria.Monitoring antimalarial drug resistance: Applying lessons learned from the past in a fast-moving present.Matrix effect elimination during LC-MS/MS bioanalytical method development.Challenges and benefits of endogenous steroid analysis by LC-MS/MS.Aspects of matrix effects in applications of liquid chromatography-mass spectrometry to forensic and clinical toxicology--a review.Recent advances in sample preparation techniques to overcome difficulties encountered during quantitative analysis of small molecules from biofluids using LC-MS/MS.Characterization of an in vivo concentration-effect relationship for piperaquine in malaria chemoprevention.Quantitative mass spectrometry methods for pharmaceutical analysis.Benefits of a pharmacology antimalarial reference standard and proficiency testing program provided by the Worldwide Antimalarial Resistance Network (WWARN).Matrix effect management in liquid chromatography mass spectrometry: the internal standard normalized matrix effect.Matrix effect explained by unexpected formation of peptide in acidified plasma.In vitro metabolism of piperaquine is primarily mediated by CYP3A4.Determination of the antimalarial drug piperaquine in small volume pediatric plasma samples by LC-MS/MS.Determination of lumefantrine in small-volume human plasma by LC-MS/MS: using a deuterated lumefantrine to overcome matrix effect and ionization saturation.An on-line solid phase extraction procedure for the routine quantification of urinary methylmalonic acid by liquid chromatography-tandem mass spectrometry.Determination of o,oEDDHA - a xenobiotic chelating agent used in Fe fertilizers - in plant tissues by liquid chromatography/electrospray mass spectrometry: overcoming matrix effects.Variability of the IS revealed ionization enhancement by bile acid in mouse plasma.Definitive Drug and Metabolite Screening in Urine by UPLC-MS-MS Using a Novel Calibration Technique.Deuterium- and Tritium-Labelled Compounds: Applications in the Life Sciences.Simultaneous determination of levonorgestrel and two endogenous sex hormones in human plasma based on LC-MS/MS.MATRIX EFFECTS IN LIQUID CHROMATOGRAPHY-MASS SPECTROMETRYIon Suppression Study for Tetracyclines in Feed
P2860
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P2860
Development and validation of a liquid chromatographic-tandem mass spectrometric method for determination of piperaquine in plasma stable isotope labeled internal standard does not always compensate for matrix effects.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Development and validation of ...... compensate for matrix effects.
@en
Development and validation of ...... compensate for matrix effects.
@nl
type
label
Development and validation of ...... compensate for matrix effects.
@en
Development and validation of ...... compensate for matrix effects.
@nl
prefLabel
Development and validation of ...... compensate for matrix effects.
@en
Development and validation of ...... compensate for matrix effects.
@nl
P1476
Development and validation of ...... compensate for matrix effects.
@en
P2093
A Annerberg
N Lindegardh
P304
P356
10.1016/J.JCHROMB.2007.12.011
P577
2007-12-24T00:00:00Z