Herpes simplex virus 1 infection induces activation and subsequent inhibition of the IFI16 and NLRP3 inflammasomes. - Wikidata - awgldk - TriplyDB

Herpes simplex virus 1 infection induces activation and subsequent inhibition of the IFI16 and NLRP3 inflammasomes.

Herpes simplex virus 1 infection induces activation and subsequent inhibition of the IFI16 and NLRP3 inflammasomes.

http://www.wikidata.org/entity/Q39191187

about

Human cytomegalovirus tegument protein pUL83 inhibits IFI16-mediated DNA sensing for immune evasion Intrinsic host restriction factors of human cytomegalovirus replication and mechanisms of viral escape Keeping it quiet: chromatin control of gammaherpesvirus latency The innate immune sensor IFI16 recognizes foreign DNA in the nucleus by scanning along the duplex.Integrating Inflammasome Signaling in Sexually Transmitted Infections Evasion of host antiviral innate immunity by HSV-1, an update Innate immune recognition of DNA: A recent history Inflammasome control of viral infection BRCA1 Regulates IFI16 Mediated Nuclear Innate Sensing of Herpes Viral DNA and Subsequent Induction of the Innate Inflammasome and Interferon-β Responses IFI16 restricts HSV-1 replication by accumulating on the hsv-1 genome, repressing HSV-1 gene expression, and directly or indirectly modulating histone modifications IFI16 Preferentially Binds to DNA with Quadruplex Structure and Enhances DNA Quadruplex Formation Herpesvirus Genome Recognition Induced Acetylation of Nuclear IFI16 Is Essential for Its Cytoplasmic Translocation, Inflammasome and IFN-β Responses Innate nuclear sensor IFI16 translocates into the cytoplasm during the early stage of in vitro human cytomegalovirus infection and is entrapped in the egressing virions during the late stage.Interleukin-36β provides protection against HSV-1 infection, but does not modulate initiation of adaptive immune responses Structure of the herpes simplex virus 1 genome: manipulation of nicks and gaps can abrogate infectivity and alter the cellular DNA damage response.Herpes simplex virus 1 counteracts viperin via its virion host shutoff protein UL41 Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA.cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection.Interleukin-1α released from HSV-1-infected keratinocytes acts as a functional alarmin in the skin.Inflammasomes.Herpes simplex virus-1 infection or Simian virus 40-mediated immortalization of corneal cells causes permanent translocation of NLRP3 to the nuclei Nutlin-3-induced redistribution of chromatin-bound IFI16 in human hepatocellular carcinoma cells in vitro is associated with p53 activation.CIB1 synergizes with EphrinA2 to regulate Kaposi's sarcoma-associated herpesvirus macropinocytic entry in human microvascular dermal endothelial cells.Barrier to auto integration factor becomes dephosphorylated during HSV-1 Infection and Can Act as a host defense by impairing viral DNA replication and gene expression Evasion of early antiviral responses by herpes simplex viruses.Regulation of inflammasome activation.Nuclear sensing of viral DNA, epigenetic regulation of herpes simplex virus infection, and innate immunity Murine Gammaherpesvirus 68 Pathogenesis Is Independent of Caspase-1 and Caspase-11 in Mice and Impairs Interleukin-1β Production upon Extrinsic Stimulation in Culture.Basal Autophagy Is Required for Herpes simplex Virus-2 Infection Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression Histone H2B-IFI16 Recognition of Nuclear Herpesviral Genome Induces Cytoplasmic Interferon-β Responses.EV71 3D Protein Binds with NLRP3 and Enhances the Assembly of Inflammasome Complex The emerging role of nuclear viral DNA sensors.A quantitative assay to monitor HSV-1 ICP0 ubiquitin ligase activity in vitro Epstein-Barr virus infection-induced inflammasome activation in human monocytes.The inflammasome NLRP3 plays a protective role against a viral immunopathological lesion.The expanding role of NLRs in antiviral immunity.Immunization with Attenuated Equine Herpesvirus 1 Strain KyA Induces Innate Immune Responses That Protect Mice from Lethal Challenge.Nuclear Innate Immune DNA Sensor IFI16 Is Degraded during Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus (KSHV): Role of IFI16 in Maintenance of KSHV Latency.Generating protective immunity against genital herpes

P2860

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P2860

Herpes simplex virus 1 infection induces activation and subsequent inhibition of the IFI16 and NLRP3 inflammasomes.

http://www.wikidata.org/entity/Q39191187

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

Herpes simplex virus 1 infecti ...... IFI16 and NLRP3 inflammasomes.

@en

Herpes simplex virus 1 infecti ...... IFI16 and NLRP3 inflammasomes.

@nl

type

label

Herpes simplex virus 1 infecti ...... IFI16 and NLRP3 inflammasomes.

@en

Herpes simplex virus 1 infecti ...... IFI16 and NLRP3 inflammasomes.

@nl

prefLabel

Herpes simplex virus 1 infecti ...... IFI16 and NLRP3 inflammasomes.

@en

Herpes simplex virus 1 infecti ...... IFI16 and NLRP3 inflammasomes.

@nl

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Journal of Virology

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Herpes simplex virus 1 infecti ...... IFI16 and NLRP3 inflammasomes.

@en

P2093

Bala Chandran

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Karen E Johnson

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Leela Chikoti

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P2860

Role of the small GTPase Rab27a during herpes simplex virus infection of oligodendrocytic cells

ICP0 antagonizes ICP4-dependent silencing of the herpes simplex virus ICP0 gene

Functional interaction between p53 and the interferon-inducible nucleoprotein IFI 16

IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes

A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway

IFI16 is an innate immune sensor for intracellular DNA

IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection

The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication

The human interferon-inducible protein, IFI 16, is a repressor of transcription

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5005-5018

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scholarly article

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10.1128/JVI.00082-13

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9

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87

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2013-02-20T00:00:00Z

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23427152

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3624293

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