DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase. - Wikidata - awgldk - TriplyDB

DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase.

DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase.

http://www.wikidata.org/entity/Q39214600

about

The CK1 Family: Contribution to Cellular Stress Response and Its Role in Carcinogenesis A cell cycle-dependent BRCA1-UHRF1 cascade regulates DNA double-strand break repair pathway choice Long noncoding RNA UPAT promotes colon tumorigenesis by inhibiting degradation of UHRF1.Limoniastrum guyonianum aqueous gall extract induces apoptosis in human cervical cancer cells involving p16 INK4A re-expression related to UHRF1 and DNMT1 down-regulation.The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis.Gender Differences in Global but Not Targeted Demethylation in iPSC Reprogramming.Casein kinase 1 suppresses activation of REST in insulted hippocampal neurons and halts ischemia-induced neuronal death.PIM1 induces cellular senescence through phosphorylation of UHRF1 at Ser311.DUB3 and USP7 de-ubiquitinating enzymes control replication inhibitor Geminin: molecular characterization and associations with breast cancer.The epigenetic integrator UHRF1: on the road to become a universal biomarker for cancer.The emerging field of epigenetics in neurodegeneration and neuroprotection.Regulation of Ubiquitin-like with Plant Homeodomain and RING Finger Domain 1 (UHRF1) Protein Stability by Heat Shock Protein 90 Chaperone Machinery.SENP8 limits aberrant neddylation of NEDD8 pathway components to promote cullin-RING ubiquitin ligase function F-box proteins in epigenetic regulation of cancer.Interaction of the epigenetic integrator UHRF1 with the MYST domain of TIP60 inside the cell.REST, a master transcriptional regulator in neurodegenerative disease.Oncogenic Y641 mutations in EZH2 prevent Jak2/β-TrCP-mediated degradation.Chromatin-Bound Cullin-Ring Ligases: Regulatory Roles in DNA Replication and Potential Targeting for Cancer Therapy.Targeting the SET and RING-associated (SRA) domain of ubiquitin-like, PHD and ring finger-containing 1 (UHRF1) for anti-cancer drug development.WDR79 mediates the proliferation of non-small cell lung cancer cells by regulating the stability of UHRF1.Thymoquinone challenges UHRF1 to commit auto-ubiquitination: a key event for apoptosis induction in cancer cells.A systems-wide screen identifies substrates of the SCF TrCP ubiquitin ligase Chromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1

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P2860

DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase.

http://www.wikidata.org/entity/Q39214600

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年学术文章

@wuu

2013年学术文章

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2013年学术文章

@zh-hans

2013年学术文章

@zh-my

2013年学术文章

@zh-sg

2013年學術文章

@yue

2013年學術文章

@zh

2013年學術文章

@zh-hant

name

DNA damage regulates UHRF1 stability via the SCF

@nl

DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase.

@en

type

label

DNA damage regulates UHRF1 stability via the SCF

@nl

DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase.

@en

prefLabel

DNA damage regulates UHRF1 stability via the SCF

@nl

DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase.

@en

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Molecular and Cellular Biology

P1476

DNA damage regulates UHRF1 stability via the SCF(β-TrCP) E3 ligase.

@en

P2093

Fei Lan

http://www.w3.org/2001/XMLSchema#string

Hao Chen

http://www.w3.org/2001/XMLSchema#string

Hiroyuki Inuzuka

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Honghui Ma

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Jianbo Diao

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Wenyi Wei

http://www.w3.org/2001/XMLSchema#string

Yang Shi

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Yujiang Geno Shi

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P2860

Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase

Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1

cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family

Critical role of the ubiquitin ligase activity of UHRF1, a nuclear RING finger protein, in tumor cell growth.

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer

SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation

Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination

The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix

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1139-1148

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scholarly article

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10.1128/MCB.01191-12

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6

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33

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