NMR mapping of the IFNAR1-EC binding site on IFNalpha2 reveals allosteric changes in the IFNAR2-EC binding site.
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Intermolecular Interactions in a 44 kDa Interferon−Receptor Complex Detected by Asymmetric Reverse-Protonation and Two-Dimensional NOESYStructural and dynamic determinants of type I interferon receptor assembly and their functional interpretation.Enhancing Pharmacokinetics, Tumor Accumulation, and Antitumor Efficacy by Elastin-Like Polypeptide Fusion of Interferon Alpha.Ligand-independent interaction of the type I interferon receptor complex is necessary to observe its biological activity.Type-1 interferons contribute to oxygen glucose deprivation induced neuro-inflammation in BE(2)M17 human neuroblastoma cells.Cytokine-receptor interactions as drug targets.The molecular basis for differential type I interferon signaling.
P2860
Q27661869-AC079AF6-C991-446B-84BB-AC69D14EA99CQ27687338-45F51A03-8538-4667-9C86-2D98B7E9ACE1Q35805537-8F126E8C-5694-4543-A90D-6F886D1B3705Q37164886-47665730-D98D-4ACF-8254-FED2A8026A67Q37717107-D94C7AC4-2DF9-4464-A598-4C3EC60EEBF5Q37771522-80E66909-D1B4-4DE2-9E10-4A6B08D5D27AQ39176574-1C505A4B-03B2-4335-ABCC-504C81BD961C
P2860
NMR mapping of the IFNAR1-EC binding site on IFNalpha2 reveals allosteric changes in the IFNAR2-EC binding site.
description
2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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name
NMR mapping of the IFNAR1-EC b ...... in the IFNAR2-EC binding site.
@en
NMR mapping of the IFNAR1-EC b ...... in the IFNAR2-EC binding site.
@nl
type
label
NMR mapping of the IFNAR1-EC b ...... in the IFNAR2-EC binding site.
@en
NMR mapping of the IFNAR1-EC b ...... in the IFNAR2-EC binding site.
@nl
prefLabel
NMR mapping of the IFNAR1-EC b ...... in the IFNAR2-EC binding site.
@en
NMR mapping of the IFNAR1-EC b ...... in the IFNAR2-EC binding site.
@nl
P2093
P2860
P356
P1433
P1476
NMR mapping of the IFNAR1-EC b ...... in the IFNAR2-EC binding site.
@en
P2093
Jacob Anglister
Jacob Piehler
Peter Lamken
Sabine Ruth Akabayov
Zohar Biron
P2860
P304
P356
10.1021/BI901313X
P407
P577
2010-02-01T00:00:00Z