Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis.
about
Prostate cancer progression and metastasis: potential regulatory pathways for therapeutic targeting.The host microenvironment influences prostate cancer invasion, systemic spread, bone colonization, and osteoblastic metastasis.Interaction of the Androgen Receptor, ETV1, and PTEN Pathways in Mouse Prostate Varies with Pathological Stage and Predicts Cancer Progression.MicroRNA-195 suppresses tumor cell proliferation and metastasis by directly targeting BCOX1 in prostate carcinoma.Low expression of BMPRIB indicates poor prognosis of breast cancer and is insensitive to taxane-anthracycline chemotherapyType II transmembrane serine proteases as potential targets for cancer therapy.Design, synthesis and biological evaluation of PSMA/hepsin-targeted heterobivalent ligands.The role of type II transmembrane serine protease-mediated signaling in cancer.Use of two gene panels for prostate cancer diagnosis and patient risk stratification.SERPINB12 Is a Slow-Binding Inhibitor of Granzyme A and Hepsin.Pericellular regulation of prostate cancer expressed kallikrein-related peptidases and matrix metalloproteinases by cell surface serine proteases.Oncogenomics of c-Myc transgenic mice reveal novel regulators of extracellular signaling, angiogenesis and invasion with clinical significance for human lung adenocarcinoma.Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion.Concurrent Hepsin overexpression and adenomatous polyposis coli deletion causes invasive prostate carcinoma in mice.Recent advances in prostate cancer research: large-scale genomic analyses reveal novel driver mutations and DNA repair defects
P2860
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P2860
Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
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2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
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2014年學術文章
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name
Targeted inhibition of cell-su ...... ostate cancer bone metastasis.
@en
Targeted inhibition of cell-su ...... ostate cancer bone metastasis.
@nl
type
label
Targeted inhibition of cell-su ...... ostate cancer bone metastasis.
@en
Targeted inhibition of cell-su ...... ostate cancer bone metastasis.
@nl
prefLabel
Targeted inhibition of cell-su ...... ostate cancer bone metastasis.
@en
Targeted inhibition of cell-su ...... ostate cancer bone metastasis.
@nl
P2093
P2860
P356
P1433
P1476
Targeted inhibition of cell-su ...... ostate cancer bone metastasis.
@en
P2093
Julian A Simon
Liem T Nguyen
Richard Leduc
Sumit S Mahajan
P2860
P304
P356
10.18632/ONCOTARGET.1817
P407
P577
2014-03-01T00:00:00Z