The structure of the extracellular region of human hepsin reveals a serine protease domain and a novel scavenger receptor cysteine-rich (SRCR) domain
about
Pro-urokinase-type plasminogen activator is a substrate for hepsinHATL5: a cell surface serine protease differentially expressed in epithelial cancersThe haptoglobin-CD163-heme oxygenase-1 pathway for hemoglobin scavengingCrystal structure of the third extracellular domain of CD5 reveals the fold of a group B scavenger cysteine-rich receptor domainCrystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase familyActive site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cationsAllosteric antibody inhibition of human hepsin proteasePla2g12b and Hpn are genes identified by mouse ENU mutagenesis that affect HDL cholesterolHepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancersIdentification and characterization of small-molecule inhibitors of hepsinThe calcium-induced conformation and glycosylation of scavenger-rich cysteine repeat (SRCR) domains of glycoprotein 340 influence the high affinity interaction with antigen I/II homologs.The cutting edge: membrane-anchored serine protease activities in the pericellular microenvironment.Membrane-anchored serine proteases in health and disease.Hepsin colocalizes with desmosomes and induces progression of ovarian cancer in a mouse model.Hepatocyte growth factor activator (HGFA): molecular structure and interactions with HGFA inhibitor-1 (HAI-1).Design, synthesis and biological evaluation of PSMA/hepsin-targeted heterobivalent ligands.Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis.Laminin-332 is a substrate for hepsin, a protease associated with prostate cancer progression.Decreased expressions of hepsin in human hepatocellular carcinomas.A split ubiquitin system to reveal topology and released peptides of membrane proteins.Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion.
P2860
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P2860
The structure of the extracellular region of human hepsin reveals a serine protease domain and a novel scavenger receptor cysteine-rich (SRCR) domain
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The structure of the extracell ...... or cysteine-rich (SRCR) domain
@ast
The structure of the extracell ...... or cysteine-rich (SRCR) domain
@en
The structure of the extracell ...... or cysteine-rich (SRCR) domain
@nl
type
label
The structure of the extracell ...... or cysteine-rich (SRCR) domain
@ast
The structure of the extracell ...... or cysteine-rich (SRCR) domain
@en
The structure of the extracell ...... or cysteine-rich (SRCR) domain
@nl
prefLabel
The structure of the extracell ...... or cysteine-rich (SRCR) domain
@ast
The structure of the extracell ...... or cysteine-rich (SRCR) domain
@en
The structure of the extracell ...... or cysteine-rich (SRCR) domain
@nl
P2093
P1433
P1476
The structure of the extracell ...... or cysteine-rich (SRCR) domain
@en
P2093
Bradley A Katz
Christine Luong
David Sperandio
John R Somoza
Joseph D Ho
Kyle Mortara
Manjiri Ghate
Mary E McGrath
Paul A Sprengeler
P304
P356
10.1016/S0969-2126(03)00148-5
P577
2003-09-01T00:00:00Z