CD27 signaling increases the frequency of regulatory T cells and promotes tumor growth.
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Immune Checkpoint Modulation in Colorectal Cancer: What's New and What to ExpectImproving Adoptive T Cell Therapy: The Particular Role of T Cell Costimulation, Cytokines, and Post-Transfer VaccinationTargeting the T-cell co-stimulatory CD27/CD70 pathway in cancer immunotherapy: rationale and potentialStimulating CD27 to quantitatively and qualitatively shape adaptive immunity to cancer.Phase I dose-escalation study of SGN-75 in patients with CD70-positive relapsed/refractory non-Hodgkin lymphoma or metastatic renal cell carcinoma.TGF-β upregulates CD70 expression and induces exhaustion of effector memory T cells in B-cell non-Hodgkin's lymphoma.Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathwayExpression of the immune regulation antigen CD70 in osteosarcoma.Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancerCharacterization of the human T cell response to in vitro CD27 costimulation with varlilumabPreclinical data on the combination of cisplatin and anti-CD70 therapy in non-small cell lung cancer as an excellent match in the era of combination therapy.Side-by-side comparison of the biological characteristics of human umbilical cord and adipose tissue-derived mesenchymal stem cells.ARGX-110, a highly potent antibody targeting CD70, eliminates tumors via both enhanced ADCC and immune checkpoint blockade.Targeting of the tumor necrosis factor receptor superfamily for cancer immunotherapy.Targeting tumor-necrosis factor receptor pathways for tumor immunotherapyTherapeutic targeting of CD70 and CD27.Harnessing co-stimulatory TNF receptors for cancer immunotherapy: Current approaches and future opportunities.CD70 and PD-L1 in anaplastic thyroid cancer - promising targets for immunotherapy.Co-stimulate or Co-inhibit Regulatory T Cells, Which Side to Go?CD70-restricted specific activation of TRAILR1 or TRAILR2 using scFv-targeted TRAIL mutants.Expression of CD70 in nasal natural killer/T cell lymphoma cell lines and patients; its role for cell proliferation through binding to soluble CD27.Metabolism-associated danger signal-induced immune response and reverse immune checkpoint-activated CD40+ monocyte differentiation.Host-Derived CD70 Suppresses Murine Graft-versus-Host Disease by Limiting Donor T Cell Expansion and Effector Function.Modulating CD27 signaling to treat cancer.Clonal expansion of renal cell carcinoma-infiltrating T lymphocytesTargeting human CD27 with an agonist antibody stimulates T-cell activation and antitumor immunity.Trial watch: Dendritic cell-based interventions for cancer therapy.Advances on regulatory T cells from the 15th International Congress of Immunology.TNF-receptor superfamily agonists as molecular adjuvants for cancer vaccines.CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy.T Cell-Derived CD70 Delivers an Immune Checkpoint Function in Inflammatory T Cell Responses.Protective role of the co-stimulator CD27 receptor and regulatory T cells in early atherogenesis.CD27 co-stimulation increases the abundance of regulatory T cells and reduces atherosclerosis in hyperlipidaemic mice.The costimulatory molecule CD70 is regulated by distinct molecular mechanisms and is associated with overall survival in diffuse large B-cell lymphoma.Terminally differentiated CD8+ T cells and CD57-FOXP3+CD8+ T cells are highly associated with the efficacy of immunotherapy using activated autologous lymphocytes.CD57 ratio as a convenient and useful immunological and prognostic parameter for stage IV carcinoma.
P2860
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P2860
CD27 signaling increases the frequency of regulatory T cells and promotes tumor growth.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
CD27 signaling increases the frequency of regulatory T cells and promotes tumor growth.
@en
CD27 signaling increases the frequency of regulatory T cells and promotes tumor growth.
@nl
type
label
CD27 signaling increases the frequency of regulatory T cells and promotes tumor growth.
@en
CD27 signaling increases the frequency of regulatory T cells and promotes tumor growth.
@nl
prefLabel
CD27 signaling increases the frequency of regulatory T cells and promotes tumor growth.
@en
CD27 signaling increases the frequency of regulatory T cells and promotes tumor growth.
@nl
P2093
P50
P1433
P1476
CD27 signaling increases the frequency of regulatory T cells and promotes tumor growth.
@en
P2093
Adrian F Ochsenbein
Christina Claus
Tamara Hilmenyuk
P304
P356
10.1158/0008-5472.CAN-11-2791
P407
P577
2012-05-24T00:00:00Z